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丙酮酸钠在缺氧型乳酸性酸中毒中的潜在临床应用 被引量:8

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摘要 丙酮酸钠(sodiumpyruvate)除少数临床试验外尚未应用于临床,因具有提高细胞缺氧耐受性(hypoxiatolerance)等诸多优异的生物学特性,适用于临床上防治缺氧型乳酸性酸中毒(LA),在重症医学上具有重要理论意义和应用价值。
出处 《中华医学杂志》 CAS CSCD 北大核心 2015年第12期958-960,共3页 National Medical Journal of China
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参考文献28

  • 1Bakker J, Nijsten MW, Jansen TC. Clinical use of lactate monitoring in critically ill patients [ J ]. Ann Intensive Care, 2013, 3:12.
  • 2Hu S, Bai XD, Liu XQ, et al. Pyruvate corrects lactic acidosis and prolongs survival during refractory hemorrhagic shock in rats [J]. J Emerg Med, 2013, 45(6) :885-893.
  • 3Nichol AD, Egi M, Pettila V, et al. Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi- centre study[J]. Crit Care, 2010, 14:1t25.
  • 4Nichol A, Bailey M, Egi M, et al. Dynamic lactate indicates as predictors of outcome in critically ill patients [ J ]. Cfit Care, 2011,15 : R242.
  • 5Puleo F, Arvanitakis M, Van Gossum A, at al. Gut failure in the ICU [ J ]. Semin Respir Crit Care Med, 2011,32 ( 5 ) : 626-638.
  • 6Kraut JA, Kurtz I. Use of base in the treatment of severe acidosis states[J]. Am J Kidney Dis, 2001, 38(4) :703-727.
  • 7Jansen TC, van Bommel J, Schoonderbeek FJ, et al. Early lactate-guided therapy in intensive care unit patients : a muhicenter, open-label, randomized controlled trial [ J]. Am J Respir Crit Care bled, 2010, 182(6) :752-761.
  • 8Zhou FQ. Pyruvate in the correction of intracellular acidosis: a metabolic basis as a novel superior buffer [ J ]. Am J Nephrol, 2005, 25(1-2) :55-63.
  • 9Flaberty DC, Hoxha B, Sun J, et al. Pyruvate-fortified fluid resuscitation improves hemodynarnic stability while suppressing systemic inflammation and myocardial oxidative stress after hemorrhagic shock [ J ]. blil bled, 2010,175 (3) : 166-172.
  • 10喻文,罗红敏,钟毓贤,周方强,谢志毅,胡森.口服丙酮酸盐糖液对致死性失血性休克大鼠脏器功能及存活率的影响[J].中华急诊医学杂志,2014,23(1):24-29. 被引量:6

二级参考文献41

  • 1胡森,夏斌,黎君友,陈廷秀,段美丽,张淑文.犬肠缺血/再灌注时小肠对早期肠内营养耐受能力的实验研究[J].中国危重病急救医学,2006,18(10):605-608. 被引量:18
  • 2Wiersinga WJ. Current insights in sepsis:from pathogenesis to new treatment targets[J].{H}CURRENT OPINION IN CRITICAL CARE,2011,(05):480-486.
  • 3Rivers E,Nguyen B,Havstad S. Early goal-directed therapy in the treatment of severe sepsis and septic shock[J].{H}New England Journal of Medicine,2001,(19):1368-1377.
  • 4O'Neill R,Morales J,Jule M. Early Goal-directed Therapy (EGDT) for severe sepsis/septic shock:which components of treatment are more difficult to implement in a community-based emergency department[J].{H}JOURNAL OF EMERGENCY MEDICINE,2012,(05):503-510.
  • 5Varpula M,Karlsson S,Ruokonen E. Mixed venous oxygen saturation cannot be estimated by central venous oxygen saturation in septic shock[J].{H}Intensive Care Medicine,2006,(09):1336-1343.
  • 6Rimachi R,Bruzzi de Carvahlo F,Orellano-Jimenez C. Lactate/pyruvate ratio as a marker of tissue hypoxia in circulatory and septic shock[J].{H}Anaesthesia and Intensive Care,2012,(03):427-432.
  • 7Sakamoto Y,Mashiko K,Matsumoto H. Selection of acute blood purification therapy according to severity scorc and blood lactic acid value in patients with septic shock[J].lndian J Crit Care Med,2010,(04):175-179.
  • 8Dellinger RP,Levy MM,Carlet JM. Surviving Sepsis Campaign:international guidelines for management of severe sepsis and septic shock:2008[J].{H}Intensive Care Medicine,2008,(01):17-60.
  • 9Levy MM,Fink MP,Marshall JC. 2001 SCCM / ESICM /ACCP/ATS/SIS International Sepsis Definitions Conference[J].{H}Intensive Care Medicine,2003,(04):530-538.
  • 10肖海鹏;杨惠玲.临床病理生理学[M]{H}北京:人民卫生出版社,200954-55.

共引文献71

同被引文献95

  • 1Qiang Sun,Jia Li,Feng Gao.New insights into insulin: The anti-inflammatory effect and its clinical relevance[J].World Journal of Diabetes,2014,5(2):89-96. 被引量:10
  • 2杨博,李树生.MODS患者胰岛素抵抗的机制[J].内科急危重症杂志,2005,11(2):90-93. 被引量:7
  • 3王汉民,连耀国,刘宏宝,孙世仁,陈威.连续性血液净化对心脏术后多脏器功能障碍综合征患者炎性介质和氧化应激的影响[J].中国血液净化,2006,5(11):769-772. 被引量:6
  • 4谭波,陈媛媛,王兴勇,许峰.大鼠MODS发病机制探讨[J].重庆医科大学学报,2007,32(10):1041-1044. 被引量:6
  • 5Kancir AS, Pleckaitiene L, Hansen TB, et al. Lack of nephrutoxicity by 6% hydroxyethyl starch 130/0.4 during hip arthroplasty: a randomized controlled trial [ J]. Anesthesiology, 2014, 121(5) : 948-958.
  • 6Rossaint J, Berger C, Kraft F, et al. Hydroxyethyl starch 130/0, 4 decreased inflammation, neutrophil recruitment, and neutrophil extracellular trap formation ~ J ]. Br J Anaesth, 2015, 114 (3) : 509- 519.
  • 7Perner A, Haase N, Winkel P, et al. Long-term outcomes in patients with severe sepsis randomised to resuscitation with hydroxyethyl starch 130/0.42 or Ringer' s acetate [ J ]. Intensive Ca~e Med, 2014, 40(7) : 927-934.
  • 8Estrada CA, Murugan R. Hydroxyethyl starch in severe sepsis: end of starch era [J]. Crit Care, 2013, 17(2): 310.
  • 9Ahnac E, Aksu U, Bezemer R, et al. The acute effects of acetate- balanced colloid and erystalloid resuscitation on renal oxygenation ina rat model of hemorrhagic shock [ J]. Resuscitation, 2012, 83 (9) : 1166-1172.
  • 10Aksu U, Bezemer R, Demirci C, et al. Acute effects of balanced versus unbalanced colloid resuscitation on renal macrocirculatory and microcirculatory perfusion during endotoxemic shock [ J]. Shock, 2012, 37(2) : 205-209.

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