急性冠脉综合征患者并发焦虑障碍与冠状动脉狭窄严重程度的相关性

Association between anxiety and severity of coronary artery lesions in patients with acute coronary syndromes

目的:探讨急性冠脉综合征(ACS)患者并发焦虑障碍患者焦虑评分与冠状动脉狭窄严重程度的关系。方法:180例ACS患者采用Zung焦虑自评量表(SAS)测试评分,分为焦虑组和非焦虑组,并行冠状动脉造影检查及心脏彩超检查测左室射血分数(LVEF),对冠状动脉病变狭窄程度进行Gensini评分,分析SAS评分与ACS患者冠状动脉病变评分(Gensini评分)的关系。结果:根据SAS评分将ACS患者分为无焦虑组82例,焦虑组98例(轻度焦虑54例,中度30例,重度14例)。焦虑组冠状动脉病变评分(Gensini评分)为(36±22)分,显著高于无焦虑组Gensini评分(25±13)分(P<0.01)。SAS评分与冠状动脉病变Gensini积分呈正相关(r=0.36,P<0.01)。结论:ACS患者焦虑障碍程度与冠脉病变狭窄程度相关。

AIM： To investigate the association between anxiety and the severity of coronary artery lesions in patients with acute coronary syndromes（ ACS）. METHODS： Self-rating anxiety scale（ SAS）and left ventricular ejection fraction（ LVEF） were measured in 180 ACS patients,who were divided into anxiety group and non-anxiety group. All patients underwent coronary artery angiography（ CAG） and the severity of coronary artery lesions were estimated by the coronary angiographic Gensini score. Correlations of the SAS score and the Gensini score were analyzed. RESULTS： According to the SAS score,82 cases were assigned to non-anxiety group and 98 cases（ mild 54 cases,moderate 30 cases,severe 14 cases） to anxiety group. The Gensini score in anxiety group was higher than the score in non-anxiety group（ 36 ±22 vs. 25 ± 13,P〈0. 01）. The SAS score was correlated with the Gensini score in ACS patients（ r =0. 36,P〈0. 01）. CONCLUSION： Degree of anxiety is correlated with the severity of coronary artery lesions and has significant prognostic value for patients with ACS.