肾癌患者CT引导下射频消融治疗后感染的因素探讨

Discussion of infection factors of renal cancer after treatment of Percutaneous Radio Frequency Ablation guided by CT

目的探讨肾癌患者CT引导下经皮射频消融(RFA)治疗后相关感染因素,并分析预防对策。方法对2010年1月-2014年1月478例行CT引导下经皮射频消融治疗肾癌患者进行临床回顾性研究,探讨术后切口感染的危险因素,采用SPSS 17.0软件进行统计分析。结果 478例肾癌患者中发生医院感染18例,感染率为3.77%;Kap-lan-Meier单因素分析显示,转移性肾癌、邻近空腔脏器、肿瘤多发、肿瘤直径>5mm与RFA术后肾内感染存在相关性(P<0.05);多因素logistic回归统计显示,继发性肿瘤、邻近空腔脏器肿瘤、多发肿瘤是术后患者出现感染的独立高危因素(P<0.05)。结论继发性肿瘤、邻近空腔脏器肿瘤、多发肿瘤等是CT引导下经皮RFA后出现肾内感染的高危因素。

OBJECTIVE To discuss the relevant infection factors of renal cancer after the treatment of PRFA guided by CT and to analyze prevention measures.METHODS A total of 478 cases of patients with renal cancer and adopted the treatment of PRFA which was guided by CT from Jan.2010 to Jan.2014 in our hospital were retrospectively studied.Risk factors of incision infections after operation were discussed.All data were analyzed by SPSS 17.0software.RESULTS Among the 478 cases of renal cancer patients,18 cases had suffered from nosocomial infections with the infection rate of 3.77%.Kap-lan-Meier single factor analysis indicated that metastatic renal cell carcinoma,neighboring hollow organs,multiple tumors and diameter of tumor more than 5mm were related to the infections within kidney after RFA operation（P〈0.05）.Multi-factor logistic regression analysis indicated that secondary tumor,tumor neighboring hollow organs and multiple tumors were the independent and high risk factors of infections after operation（P〈0.05）.CONCLUSIONSecondary tumor,tumor neighboring hollow organs and multiple tumors were the high risk factors of infections within kidney after PRFA guided by CT.