受血患者血清感染性指标检测与分析

Detection and analysis on serum indicators of infections in blood recipients

目的探讨输血患者受血前血清感染性指标的阳性率及分布,为临床输血方法指导建议。方法对2012年1月-2013年12月11 279例受血前患者使用化学发光法检测包括抗丙型肝炎病毒抗体(HCV)、人体免疫缺陷病毒抗体(Anti-HIV)、苍白密螺旋体抗体(Anti-TP),同时使用时间分辨免疫荧光法进行乙型肝炎病毒表面抗原(HBsAg)检测,分析阳性率及不同科室阳性率分布。结果乙型肝炎表面抗原阳性569例,阳性率5.04%;2例HIV抗体检测阳性患者均出现在产科,梅毒检测阳性主要出现在妇科。结论输血患者受血前血清感染性指标存在一定阳性比例,应加强筛选,及时发现潜在感染源,提高安全性。

OBJECTIVE To investigate the positive rate and the distribution of serum indexes of blood infections before transfusion so as to put forward advice for clinical transfusion methods.METHODS Totally 11279 patients before blood transfusion from Jan.2012 to Dec.2013 were performed with chemiluminescence detection for antihepatitis C virus antibody（hepatitis C virus,HCV）,human immunodeficiency virus antibody（anti-HIV）,Treponema pallidum antibody（anti-TP）,at the same time,the time-resolved fluorescence immunoassay was used for hepatitis B virus surface antigen（HBsAg）detection,the positive rate and the positive rate distribution in different departments were analyzed.RESULTS The hepatitis B surface antigen was positive in 569 patients,the positive rate was 5.04%,2cases of HIV antibody positive patients appeared in the obstetric department,the positive syphilis detection mainly appeared in the gynecologic department.CONCLUSIONIndexes of infection in patients before transfusion are positive in certain proportion,clinician should strengthen the screening and discover the potential sources of infections,so as to improve safety.