Smart Plug泪小管塞治疗水液缺乏型干眼症临床初步观察

Preliminary clinical observation of Smart Plug canalicular plug for the treatment of aqueous-deficient dry eye

目的:探讨Smart Plug泪小管塞治疗水液缺乏型干眼症临床疗效。方法:选取2012-05/2013-04期间我院收治的48例水液缺乏型干眼症患者为研究对象,进行Smart Plug泪小管塞治疗,观察术后临床疗效、基础泪液分泌试验(SchirmerⅠtest,SⅠt)、泪膜破裂时间(tear break up time,BUT)、角膜荧光素染色(fluoreseein staining,FL)变化。结果:本组48例患者,显效31例(65%),有效14例(29%),无效3例(6%),总有效率为94%。治疗前,患者SⅠt,BUT,FL分别为3.49±1.24mm/5min,3.15±1.07s,2.52±0.11分。治疗后,患者SⅠt,BUT,FL均明显改善,与治疗前比较,差异具有统计学意义(P<0.05)。1例患者术后有异物感,8h后栓子脱落;1例患者于术后8mo出现肉芽组织,泪小管塞脱落。其余病例无下泪小管感染或肉芽肿。结论:Smart Plug泪小管塞治疗水液缺乏型干眼症疗效确切,能够有效缓解临床症状,值得临床推广。

AIM： To discuss the effect of Smart Plug canalicular plug on aqueous- deficient dryeye.METHODS： Forty- eight cases of aqueous- deficient dry eye patients in our hospital from May 2012 to April2013 were selected for the study. After treated by Smart Plug canalicular plug, postoperative clinical efficacy,foundation Schirmer I test（ SIt）,tear film break- up time（ BUT）,corneal fluorescein staining（ FL） changes were observed.RESULTS： Forty- eight patients were cured,31 cases were markedly effective（ 65%）,effective 14 cases（ 29%）,invalid in 3 cases（ 6%）,the total effective rate was 94%.Before treatment,SⅠ t,BUT,and FL was（ 3. 49 ± 1. 24）mm /5min,（ 3. 15 ± 1. 07） s,and（ 2. 52 ± 0. 11） points,respectively. After treatment, SIt, BUT, FL were significantly improved compared with before treatment,the difference was statistically significant（ P 〈 0. 05）. One patient had postoperative foreign body sensation,8h after shedding emboli; One patient granulation tissue after surgery 8mo,canalicular plug off. The remaining cases had no inferior lacrimal duct infection or granuloma.CONCLUSION： Smart Plug canalicular plug is an effective treatment for aqueous- deficient dry eye,can effectively relieve symptoms,worthy of promotion.