2011～2013年广西孕产妇梅毒检测结果分析

Analysis of tests of syphilis among maternal women in Guangxi from 2011 to 2013

目的了解广西孕产妇梅毒感染情况,为制定梅毒母婴传播干预政策提供依据。方法对首次产检建卡和住院分娩的孕产妇进行免费快速血浆反应素环状卡片试验（RPR）或甲苯胺红不加热血清试验（TRusrt）筛查,试验结果呈阳性者采用梅毒螺旋体明胶颗粒凝集试验（TPPA）进行确认。收集2011～2013年预防艾滋病梅毒和乙肝母婴传播信息系统月报表,应用SPSS13.0统计软件进行数据分析。结果 2011年、2012年、2013年全区孕产期接受梅毒检测的孕产妇数分别为798 305人、924 622人和852 306人,三年合计筛查2 575 233人,孕产妇梅毒检测率分别为96.12%、99.55%、99.84%,呈逐年上升趋势。2011年、2012年、2013年发现感染梅毒孕产妇总数分别为1 778人、870人和1 410人,孕产妇梅毒检出率分别为0.22%、0.09%和0.17%,2013年较2012年上升了近一倍。孕产妇孕期梅毒检测率2013年较2011年上升了24.03%。仅产时梅毒检测率2013年较2011年下降了78.26%。2011年、2012年、2013年仅产时梅毒检出率分别为0.47%、0.55%、0.67%。感染产妇所娩活产数2011年、2012年、2013年分别为1 741人、862人、1 406人,合计4 009人。结论对孕产妇进行梅毒检测有利于发现隐性梅毒,广西孕产妇梅毒感染有逐年增加趋势,应加强梅毒感染孕产妇及所生婴儿的规范治疗、定期随访和科学管理,以控制梅毒母婴传播。

Objective To explore the conditions of syphilis infection among maternal women in Guangxi and provide scientific evidence for making policy to intervene in mother-to-child transmission of syphilis. Methods Rapid plasma Reagin Test（ RPR） and Toluidine Red unheated Serum Test（ TRusrt） were used to screen syphilis infections in the prenatal maternal and hospital delivery women. Trepmen Pauidum Particle Agglutination（ TPPA） was applied to confirm the results. Results 2 575 233 pregnant women were included in the study. The testing numbers were 798 305,924 622 and 852 306 respectively from 2011 to 2013 in Guangxi. The detection rates had a rising trend year by year which were 96. 12%,99. 55% and 99. 84% from 2011 to 2013,the positive rates were 0. 22%,0. 09% and 0. 17%respectively from 2011 to 2013. The positive rate in 2013 was twice as many as that in 2012. The proportion of syphilis detection in pregnant women was 24. 03% higher in 2013 than that in 2011. The proportion of intrapartum detection was decreased by 78. 26% in 2013 compared with that in 2011. The positive rates of intrapartum detection were respectively 0. 47%,0. 55% and 0. 67% from 2011 to 2013. Conclusion Maternal syphilis infection has increased year by year in Guangxi. It is necessary to strengthen standard treatment of the maternal syphilis infection and their birth-infant,and follow-up on a regular basis and scientific management to control the syphilis mother-to-child transmission.