组织工程补片及3D打印技术在盆腔重建手术中的应用前景

The application prospect of tissue-engineered mesh with 3D printing technique in the pelvic floor reconstructive surgery

手术是重度盆腔器官脱垂主要的治疗方式。目前补片是盆底手术的焦点,聚丙烯补片虽能明显减低复发率,但有侵蚀、暴露、感染等副反应,生物源性补片虽有很好的组织相容性,但支持能力不强。目前,应用组织工程学及3D打印技术开发研制新型补片是研究热点。文章综述了目前国内外组织工程补片的研究现状及应用前景。

Mesh surgery is the main therapy method for pelvic organ prolapse（POP）.Synthetic mesh has the advantage of low recurrence rate but has the risk of erosion, exposure and infection.Biological mesh has better histocompatibility but is not strong enough.Tissue-engineered mesh with 3D printing technique is the key research point currently. Here we overview the studies and application prospect of tissue-engineered mesh.