期刊文献+

A novel 12,23-epoxy dammarane saponin from Panax notoginseng 被引量:10

A novel 12,23-epoxy dammarane saponin from Panax notoginseng
原文传递
导出
摘要 The present study investigated the chemical constituents of the roots and rhizomes of Panax notoginseng.Compounds were isolated by various column chromatographic methods,and their structures were elucidated by the extensive analysis of spectroscopic data and chemical evidences.A novel 12,23-epoxy dammarane-type saponin,named epoxynotoginsenoside A(1),together with four known compounds(2-5),was isolated and characterized. The present study investigated the chemical constituents of the roots and rhizomes of Panax notoginseng. Compounds were isolated by various column chromatographic methods, and their structures were elucidated by the extensive analysis of spectroscopic data and chemical evidences. A novel 12, 23-epoxy dammarane-type saponin, named epoxynotoginsenoside A (1), together with four known compounds (2-5), was isolated and characterized.
出处 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2015年第4期303-306,共4页 中国天然药物(英文版)
基金 supported by the grants from the Research Committee of the University of Macao(MYRG123-ICMS12) Macao Science and Technology Development Fund(SKL/QRCM/EST/11-Y3/ICMS) National Natural Science Foundation of China(S2013HT 0003L)
关键词 PANAX notoginseng DAMMARANE SAPONIN Epoxynotoginsenoside A Panax notoginseng Dammarane saponin Epoxynotoginsenoside A
  • 相关文献

参考文献16

  • 1State Administration of Traditional Chinese Medicine. Zhong- huabencao [M]. Shanghai Science and Technology Publishing Company, 1998: 839-850.
  • 2Wan JB, Li P, Yang RL, Zhang QW, et al. Separation and puri- fication of 5 saponins from Panax notoginseng by preparative high-performance liquid chromatography [J]. J Liquid Chromt Rel Techn, 2013, 36(3): 406-417.
  • 3Wan JB, Zhang QW, Hong S J, et al. Chemical investigation of saponins in different parts of Panax notoginseng by pressurized liquid extraction and liquid chromatography-eleetrospray ioni- zation-tandem mass spectrometry [J]. Molecules', 2012, 17(5): 5836-5853.
  • 4Qian ZM, Wan JB, Zhang QW, et al. Simultaneous determi- nation of nucleobases, nucleosides and saponins in Panax notoginseng using multiple columns high performance liq- uid chromatography [J]. J Pharmceut Biomed, 2008, 48(5): 1361-1367.
  • 5Wan JB, Zhang QW, Ye WC, et al. Separation and purification of protopanaxatriol and protopanaxadiol type saponins from Panax notoginseng with macroporous resins [J]. Sep Purif Technol, 2008, 60(2): 198-205.
  • 6Sun HX, Qin F, Ye YR Relationship between haemolytic and adjuvant activity and structure ofprotopanaxadiol-type saponins from the roots of Panax notoginseng [J]. Vaccine, 2005, 23(48-49): 5533-5542.
  • 7Sun S, Wang CZ, Tong R, et al. Effects of steaming the root of Panax notoginseng on chemical composition and anticancer activities [J]. FoodChem, 2010, 118(2): 307-314.
  • 8Zhao Y, Wang W, Han L, et al. Isolation, structural determination, and evaluation of the biological activity of 20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol [20(S)- 25-OCH3-PPD], a novel natural product from Panax notoginseng [J]. Med Chem, 2007, 3(1): 51-60.
  • 9Yang CY, Wang J, Zhao Y, et aL Anti-diabetic effects of Panax notoginseng saponins and its major anti-hyperglycemic components [J]. J Ethnopharmaeol, 2010, 130(2): 231-236.
  • 10Uzayisenga R, Ayeka PA, Wang Y. Anti-diabetic potential of Panax notoginseng saponins (PNS): A review [J]. Phytother Res 2013, doi: 10.1002/ptr.5026.

同被引文献261

引证文献10

二级引证文献201

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部