摘要
目的:探讨影响直肠癌患者术后生存状况的相关因素。方法:回顾性调查2007年2月—2010年5月直肠癌患者93例,进行问卷调查结合患者住院期间相关资料,统计分析患者生存时间及生存质量评分,采用Log-rank单因素分析及C ox比例风险回归分析,确定影响直肠癌患者术后生存状况的相关因素。结果:93例直肠癌患者中,术后生存时间0.5~7年,平均(1.51±0.24)年,2年生存36例,2年生存率38.71%。患者生存状况与性别、受教育程度、高血压、糖尿病、术前C EA水平没有显著相关性(P〉0.05),而与年龄、收入情况、负性情绪事件、肿瘤大小、淋巴结转移、浸润深度、手术方式、化疗与否有关(P〈0.05)。结论:直肠癌患者术后生存状况与多方面因素相关,在患者诊断及治疗过程中,要综合考虑各因素在疾病进展及预后中的作用。
Objective: To investigate the living condition related factors for patients after colorectal cancer surgery, and provide a reliable basis for assessing the prognosis of the disease.Methods: A retrospective survey approach selected in February 2007 to May 2010 to colorectal cancer patients in our hospital for treatment of 93 cases of general surgery, patients or their fam ilies in the form of questionnaires collected history, com bined with the relevant period of hospitalization inspection, statistical analysis survival time and quality of life score, using the Log-rank univariate analysis and the Cox proportional hazards regression analysis to identify factors affecting survival of patients with colorectal cancer. Results: 93 cases of colorectal cancer patients, survival time after surgery for up to sevenyears, a minimum of six months, the median time was(1.51 ± 0.24)years,2-year survivalof36 cases, 2-year survivalrate of 38.71%. Patients living conditions and gender, educationallevel, hypertension, diabetes, preoperative C EA levels were notsignificantly correlated(P〈0.05), but not with age, incom e, negative em otional events, tum or size, lymph node metastasis,depth of invasion, surgical, chem otherapy or not(P〉0.05)related. Conclusion: Patients with colorectalcancer after surgery survivalwas associated with many factors in the diagnosis and treatment of patients, and com prehensive consideration of various factors on disease progression and prognosis in the role.
出处
《中国现代普通外科进展》
CAS
2015年第2期123-126,共4页
Chinese Journal of Current Advances in General Surgery
关键词
直肠肿瘤
生存状况
回归分析
Colorectalneoplasms·Survival·Logistic regression analysis