真皮下血管网皮瓣成活质量的实验研究

An Experimental Study on Survival Quality of Subdermal Vascular Network Flap

目的:探讨真皮下血管网皮瓣成活质量。方法:选择健康家猪10只,设计真皮下血管网皮瓣40个(实验组),传统皮瓣40个(对照组),比较术后8 d家猪两侧皮瓣的成活长度和面积,通过大体观察及组织学检测比较两组皮瓣的成活质量。结果:术后8 d,实验组皮瓣成活长度均值以及成活面积均大于对照组,差异有统计学意义(P<0.05);成活质量,实验组与对照组均成活稳定,质量好,近蒂端皮瓣结果清晰,胶原纤维排列有序,两组皮瓣在术后2 d中远端即出现表皮细胞变性、坏死;实验组皮瓣中远端皮瓣存活3例,坏死35例,对照组38例中远端全部坏死。结论:真皮下血管网皮瓣近蒂端成活质量好,中远端成活质量不稳定。

Objective： To investigate the survival quality of subdermal vascular net flap. Methods：Ten pigs were selected to design and make 40 subdermal vascular net skin flaps（ experimental group）and 40 traditional skin flaps（ control group） both on bodies of these pigs. In 8 days after the operation,the survival lengths and areas of the flaps on both sides of pigs were compared and the survival quality of flaps of the two group was compared by gross observation and histological test. Results： In 8days after operation,the average survival length and area of flaps in experimental group were longer and larger than those of flaps in control group,and the differences were statistically significant（ P〈0. 05）. Flaps in both groups showed good survival quality,the flaps near the pedicle were clear and collagen fibers were arranged in an orderly manner. In 2 days after operation,in both experimental group and control group,epidermal cell degeneration,and necrosis happened in the middle and farend from pedicle. Three middle and far-end flaps survived and 35 necrosed in experimental group,while 38 middle and far-end flaps in control group necrosed. Conclusion： Subdermal vascular net flap near the pedicle exhibit good survival quality,but middle and far-end flaps are unstable.