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HC-Ⅱ检测在ASCUS分流中的作用

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摘要 目的:探讨检测高危型人乳头状瘤病毒(HR-HPV)载量在宫颈不明确意义非典型鳞状细胞(ASCUS)临床分流管理的作用及意义。方法:对89例ASCUS患者进行HC-Ⅱ检测及阴道镜下宫颈活检,比较不同HR-HPV载量下宫颈病变情况。结果:宫颈上皮内瘤变(CIN)检出率46.1%(41/89),HR-HPV阳性组检出率60.0%(33/55),明显高于HR-HPV阴性组23.5%(8/34),差异有统计学意义(P<0.05);HR-HPV阳性组上皮内高度病变(CINⅡ及以上病变)检出率32.7%(18/55),高于HR-HPV阴性组8.8%(3/34),差异有统计学意义(P<0.05);不同HR-HPV载量下CIN检出率差异无统计学意义(P>0.05)。结论 :CIN的发生与HR-HPV感染密切相关,与HR-HPV载量未见明显剂量-反应关系。
作者 陶秀坤 李存肖 谭志云
机构地区 广东省深圳市职业病防治院
出处 《实用中西医结合临床》 2015年第2期69-70,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
关键词 人乳头状瘤病毒 不明确意义非典型鳞状细胞 宫颈上皮内瘤变
分类号 R711.32 [医药卫生—妇产科学]
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参考文献6

  • 1Schiffman M,Solomon D.Findings to date from the ASCUS-LSIL Triage Study(ALTS)[J].Arch Pathol Lab Med,2003,127(8):946-947.
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二级参考文献8

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实用中西医结合临床
2015年 第2期

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