皮下乳腺切除术治疗乳腺增生伴癌症临床分析

Analysis on Subcutaneous Mastectomy in the Treatment of Mammary Gland Proliferation Combined with Breast Cancer

目的:探讨皮下乳腺切除术治疗乳腺增生伴癌症的临床疗效和预后分析。方法:随机选取2009年1月至2012年2月在我院就诊乳腺增生伴癌症女性患者68例,均为已婚已育女性,随机分为观察组和对照组,观察组35例给予乳房切除术治疗,对照组33例给予药物保守治疗,观察并比较两组的临床疗效、美容效果和预后情况。结果:观察组临床有效率高达88.57%,显著高于对照组(66.67%)(P<0.05);观察组美容效果良好率为74.29%显著高于对照组(30.30%)(P<0.01);观察组局部复发率、再住院率和死亡率均低于对照组,差异具有统计学意义(P<0.05)。结论:乳腺切除术治疗乳腺增生伴癌症不但安全性高、操作简便、疗效显著、预后好,而且能满足形体要求又能保留其乳腺功能,值得临床进一步的推广和研究。

Objective： To discuss the curative effect and prognosis of subcutaneous mastectomy in the treatment of mammary gland proliferation combined with breast cancer. Methods： 68 cases of patients of mammary gland proliferation combined with breast cancer between January 2009 and February 2012 in our hospital were selected and divided into the observation group（35cases） and the control group（33 cases）. Observation group received subcutaneous mastectomy,while the contol group received conservative drug therapy, clinical efficacy, cosmetic effect and prognosis of the two groups were observed and compared. Results： The clinical efficiency of the observation group is significantly higher than that of the control group（P〈0.05）; The cosmetic effect of observation group was significantly better than that of the control group（P〈0.01）; Local recurrence rate, re-hospitalization rate and mortality in observation group were significantly lower than those of control group（P〈0.05）. Conclusion： The subcutaneous mastectomy not only has high safety,easy operation, obvious curative effect and good prognosis,but also can retain the integrity of breast and the mammary gland function. It is worthy of clinical promotion and further research.