三唑酰胺1,4-戊二烯-3-酮衍生物的合成及生物活性

Synthesis and Biological Activity of Novel Triazoleamide-1,4-Pentadien-3-one Derivatives

以丙酮和水杨醛为起始原料,设计合成了9个新型含氟1,2,4-三唑酰胺姜黄素类化合物,通过1H NMR、19F NMR、IR及元素分析等技术手段对目标化合物进行了结构表征。采用Airbrush喷雾法进行生物活性测试,结果表明部分化合物具有不同程度的杀虫活性。

Using acetone and 2-hydroxybenzaldehyde as starting materials, nine novel curcumin derivatives containing 1,2,4-triazole and amide units were synthesized. The structures were confirmed by ^1H NMR, ^19F NMR, IR and elemental analysis. The preliminary result of bioassay by airbrush spraying shows that some of the compounds obtianed exhibit weak to moderate insecticidal activity.