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帕金森病与糖尿病相关性研究进展 被引量:4

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摘要 帕金森病是一种常见于中老年人的神经退行性疾病。糖尿病患者可因高血糖及胰岛素抵抗导致多巴胺能神经元受损、多巴胺合成障碍从而引起帕金森病。本文综述了帕金森病与糖尿病具有相关性的依据以及糖尿病通过代谢、氧化应激、蛋白质糖基化、细胞因子等方面增加帕金森病发病风险的病理生理学机制,最后对该相关性进行了总结,并进一步提出了其在帕金森病治疗上的应用前景。
作者 陈泽响 陆磊
出处 《国际神经病学神经外科学杂志》 北大核心 2015年第1期81-84,共4页 Journal of International Neurology and Neurosurgery
基金 上海市卫生局(2010095)
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