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运动疗法防治2型糖尿病作用机制的研究进展 被引量：2

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摘要 糖尿病是严重危害人类健康的最常见的疾病之一，其中2型糖尿病（T2DM）患者占90%-95%，估计到2025年全世界T2DM患者将达到3亿左右。运动疗法是糖尿病最重要的防治方法之一，尤其适宜T2DM患者的防治，具有易操作、受环境限制少、费用低、副作用少等优点。近年来，关于运动疗法防治T2DM及其并发症的作用机制研究较多，现将这些研究结果综述如下。
作者 吴毅 吴军发
机构地区 复旦大学附属华山医院康复医学科
出处 《中华糖尿病杂志》 CAS CSCD 2015年第3期184-186,共3页 CHINESE JOURNAL OF DIABETES MELLITUS
基金 国家自然科学基金课题（30370685,39970841）
关键词 2型糖尿病 运动疗法 防治 T2DM 人类健康 患者 副作用 并发症
分类号 R587.1 [医药卫生—内分泌]
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参考文献20

  • 1Qatanani M,Lazar MA. Mechanisms of obesity?associated insulin resistance: many choices on the menu[J]. Genes Dev,2007,21(12):1443-1455.
  • 2Christine K?nner A,Brüning JC. Toll-like receptors: linking inflammation to metabolism[J]. Trends Endocrin Met,2011,22(1):16-23.
  • 3Malenfant P,Tremblay A,Doucet E,et al. Elevated intramyocellular lipid concentration in obese subjects is not reduced after diet and exercise training[J]. Am J Physiol Endocrinol Metab,2001,280(4):E632-639.
  • 4Horowitz JF. Fatty acid mobilization from adipose tissue during exercise[J]. Trends Endocrin Met,2003,14(8):386-392.
  • 5Cai D,Yuan M,Frantz DF,et al. Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-КB[J]. Nat Med,2005,11(2): 183-190.
  • 6Gleeson M,Bishop NC,Stensel DJ,et al. The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease[J]. Nat Rev Immunol,2011,11(9):607-615.
  • 7Charles BA,Doumatey A,Huang HX,et al. The roles of IL-6,IL-10,and IL-1RA in obesity and insulin resistance in african-americans[J]. J Clin Endocrinol Metab,2011,96(12):E2018-2022.
  • 8Cerf ME. Beta cell dysfunction and insulin resistance[J]. Front Endocrinol,2013,4(37):1-12.
  • 9Beaudry JL,Riddell MC. Effects of glucocorticoids and exercise on pancreatic β-cell function and diabetes development[J]. Diabetes Metab Res Rev,2012,28(7):560-573.
  • 10Teixeira de Lemos E,Reis F,Baptista S,et al.Exercise training decreases proinflammatory profile in Zucker diabetic(type 2)fatty rats[J]. Nutrition,2009,25(3):330-339.

二级参考文献9

  • 1[1]DeFronzo RA, Jacot E, Jequier E,et al. The effect of insulin on the disposal of intravenous glucose results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes,1981,30:1000-1007
  • 2[2]Fink P, Wallace P, Brechtel G, et al. Evidence that glucose transport is rate limiting for in vivo glucose uptake. Metabolism, 1992, 41:897-902.
  • 3[3]Ploug T, Stallknecht BN, Pedersen D, et al. Effect of endurance training on Glucose transport capacity and glucose tranporter expression in rat skeletal muscle. Am J Physiol, 1990, 259:E778-E786.
  • 4[4]James D, Strube M, Mueckler M, et al. Molecular cloning and char acte rization of an insulin-regulatable glucose transporter. Nature, 1989, 338:8 3-87.
  • 5[5]Klip A, Ramlal T, Young AJ, et al. Insulin-induced translocation of glucose transporters in rat hindlimb muscles. FEBS Lett, 1987,244:224-230.
  • 6[6]Lowery OH, Rosebrough HJ, Farr AL, et al. Protein measurement with the folinphenol reagent, J Biol Chem, 1951,193:265-275.
  • 7[7]Marette A, Richardson JM, Ramlal T, et al Abundance, localization, and insulin-induced translocation of glucose transporters in red and white muscle. Am J Phsiol 1992, 263:C443-452.
  • 8[8]Douen AG, Ramlal T, Rastogi S, et al. Exercise induces recruitment of the "insulin-responsive glucose transporter" evidence for distinct intracellula r insulin and exercise-recruitable transporter pools in skeletal muscle. J Bio Chem, 1990, 265: 13427-13430.
  • 9[9]Lund S, Holman GD, Schnitz O, et al. Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin . Proc Natl Acad Sci USA 1995, 92:5817-5821.

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二级引证文献22

中华糖尿病杂志
2015年 第3期

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