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分化型甲状腺癌相关基因研究进展 被引量：3

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摘要 甲状腺癌是头颈外科及内分泌科最常见的恶性肿瘤,近年来在我国其发病率有上升趋势。2012年,甲状腺癌发病率为6.56/10万人。分化型甲状腺癌（differentiated thyroid carcinoma,DTC）起源于滤泡上皮细胞,是甲状腺癌中最常见的病理组织类型,占甲状腺恶性肿瘤的90%以上,其又分为乳头状癌（papillary thyroid carcinoma,PTC）和滤泡状癌（follictalar thyroid carcinoma , FTC）.
作者 郝智 崔建英
机构地区 保定市肿瘤医院头颈外科 保定市肿瘤医院神经内科
出处 《中国肿瘤临床与康复》 2015年第4期511-512,共2页 Chinese Journal of Clinical Oncology and Rehabilitation
关键词 甲状腺肿瘤 弥漫性 基因 Thyroid neoplasms Diffuse Gene
分类号 R736.1 [医药卫生—肿瘤]
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参考文献23

  • 1Hundahl SA,Fleming ID,Fremgen AM,et al.A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S.,1985-1995 [J] .Cancer,1998,83:2638-2648.
  • 2Kodama Y,Asai N,Kawai K,et al.The RET protooncogene:a molecular therapeutic target in thyroid cancer[J] .Cancer Sci,2009,96:143-148.
  • 3Rabes HM.Gene rearrangement in radiation—reduced thyroid carcinogenesis[J] .Med Pediatr Oncol,2001,36:574-582.
  • 4Nikiforov YE.RET/PTC rearrangement in thyroid tumors[J] .Endocr Pathol,2012,13:3-16.
  • 5Zafon C,Obiols G,Castellvl J,et al.Clinical significance of RET/PTC and p53 protein expression in sporadic papillary thyroid carcinoma [J] .Histopathology,2007,50:225-231.
  • 6Mayr B,Potter E,GoRETzki P,et al.Prognostic value of RETprotooncogene activation in papillary thyroid carcinoma[J] .J Endocrinol Invest,1996,19 (Supp1)6:67.
  • 7Missero C,Pirro MT,Di Lauro R.Multiple RAS downstream pathways mediate functional repression of the homeobox gene product TTF-I[J] .Mol Ce I1 Biol,2000,20:2783-2793.
  • 8Knanf JA.Kuroda h.Basu S,et al.RET/PTC-induced dedifferentiation of thyroid cells is mediated throughY 1062 signaling through SHC-RAS-MAP kinase[J] .Oncogene,2003,22:4406-4412.
  • 9Avvedimento VE,Musti AM,Ueffing M,et al.Reversible inhibition of a thyroid specmc traps-acting factor by RAS[J] .Genes Dev,1991,5:22-28.
  • 10Gallo A, Benusiglio E, Bonapace IM, et al. v-RAS and protein kinase C dedifferentiate thyroid cells by down-regulating nuclear cAMP-dependent protein kinase A [ J ]. Genes Dev, 1992,6: 1621-1630.

同被引文献33

  • 1王池平,乔茜伟,包建东.重组人促甲状腺激素介导^(131)I治疗分化型甲状腺癌的疗效分析[J].中国生化药物杂志,2014,34(4):95-97. 被引量：4
  • 2Machens A, Lorenz K, Sekulla C, et al. Molecular epidemiology of multiple endocrine neoplasia 2 : implications [or RET screening in the new millenniuml-J3. Eur J Endocrinol, 2013,168(3) : 307-314.
  • 3Zhong H, De Marzo AM, Laughner, et al. Overexpression of hypoxia-inducible factor-1 alpha in common human cancers and their metastasesEJ~.Caneer Res,1999,59(6) :5830-5835.
  • 4Sassolas G, Hafdi-Nejjari Z, Sch6tt AM, et al. Geographical correlation between incidence of benign disease and that of cancer of the thyroid among the population of the Rh ne-Alpes.R~gion of France[J]. Eur J Endocrinol,2010,162(1) : 127-135.
  • 5Uchida K, Yonezawa M, Nakamura S, et al. Impaired neuro- genesis in the growth-retarded mouse is reversed by T3 treat- ment[J]. Neuroreport, 2005,16(2) : 103-106.
  • 6Osmak-Tizon L, Poussier M, Cottin Y, etal. Non-genomic ac- tions of thyroid hormones:Molecular aspects[J]. Arch Cardio- vasc Dis,2014,107(4)~207-211.
  • 7Jia S, Yu J, Zhang D, et al. Expression and regulation of am- phiregulin in Gsa-mutated human bone marrow stromal cells of fibrous dysplasia of mandible[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2011,111 (5) : 618-626.
  • 8Lee JW, Chen JY, Yang CS, Doong SL. Thyroid hormone re- ceptor alpha 1 (c-erb A alpha 1) suppressed transforming phe- notype o~ nasopharyngeal carcinoma cell line[J]. Cancer Lett, 2002,184(2) .. 149-156.
  • 9Plateroti M, Kress E, Mori JI, et al. Thyroid hormone receptor alpha1 directly controls transcription of the beta-catenin gene in intestinal epithelial cells[J]. Mol Cell Biol, 2006, 26 (8): 3204-3214.
  • 10Guigon CJ, Zhao L, Lu C, et al. Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor[J]. Mol Cell Biol,2008,28(14) :4598-4608.

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中国肿瘤临床与康复
2015年 第4期

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