气流受限与肺癌的相关性研究

A Study of the Relation between Airflow Obstruction and the Risk of Lung Cancer

目的分析气流受限与肺癌危险性的关系。方法对本院新确诊的648例肺癌患者及663例从未惠肺癌的患者作为对照组进行对照分析研究。结果合并慢性阻塞性肺疾病的患者,肺癌发生的OR值明显升高,为3.07。当FEV1%<60%时,肺癌发生的OR值为2.50。当FEV1/FVC%<50%肺癌发生的OR值为2.77。结论气流受限是肺癌发生的一项独立危险因素,随着肺功能损伤的加重,肺癌发生的危险性明显增高;合并慢性阻塞性肺疾病的患者,肺癌发生的危险性明显增高。

[ ABSTRACT] Objective To analyze the relationship between airflow obstruction and the risk of lung cancer . Methods The analysis was based on the data collected in the Second People＇s Hospital of Weifang .Six hundred and for-ty-eight cases of newly diagnosed patients with lung cancer and 663 patients without lung cancer selected as control group were compared for case-control study .Results The patients with COPD had an increased risk of lung cancer ,OR=3. 07.When FEV1 was lower than 60%,the risk of lung cancer increased （OR=2.50）.And when FEV1/FVC was lower than 50%,the risk of lung cancer increased （OR=2.77）,too.Conclusion The airflow obstruction is an independent risk factor for lung cancer and the risk of lung cancer can increase obviously with the impairment of lung function ,be-sides patients with a history of COPD have a higher risk of lung cancer .