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融水小型猪F1代的血常规、血生化与电解质指标 被引量:8

Detection and analysis of blood parameter,blood biochemical and electrolyte indices in F1 generation of Rongshui miniature pig
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摘要 目的测定融水小型猪(rongshui miniature pig,RMP)F1代血常规、血生化与电解质指标。方法选取4月龄F1代RMP 85头,雌性43头、雄性42头;12月龄36头,雌雄各半。颈静脉采血,分析血常规、血生化与电解质等22项指标。结果融水小型猪相同月龄时,两性别的血常规指标、血生化和电解质的大部分指标差异不大,但同性别在不同月龄之间的部分指标差异明显。12月龄比4月龄融水小型猪,血常规指标中的白细胞数、血小板数下降,血红蛋白含量升高(P<0.05),而红细胞数变化不大(P>0.05);血清ALT、AST、ALP、CK(雄性)、LDH(雄性)A/G、BUN、GLU(雌性)、CHOL(雄性)和K+下降(P<0.05);血清总蛋白、TBIL、CR、Ca2+升高(P<0.05),而血清CHOL(雌性)、TG,HDL-C,LDL-C变化不大。有19项生化、电解质指标在或接近人类正常值范围,占86.4%(19/22)。结论融水小型猪的部分血常规、大部分血生化与电解质指标与人类正常值接近。 Objective To detect the blood parameter, blood biochemical and electrolyte indices of the F1 generation of Rongshui miniature pig (RMP). Methods The blood of 43 female and 42 male RMPs of 4'h month old, and 36 RMPs of 12th month old (half male and female) were extracted from jugular vein. And the blood parameter, blood biochemical and electrolyte indices were detected by blood analyzer and automatic biochemical analyzer. Results In the same month-old RMP, no significant difference between male and female were found in most indices of blood parameter,blood biochemical and electrolyte indices. On the other hand, many indices were difference between 4th month old and 12th month old RMPs of same gender. Compared with the 4th month old RMP, the 12th month old RMP decreased significantly in WBC and PLT, increased in HGB (P 〈 0.05) while RBC was the same (P 〉 0.05). Serum ALT, AST, ALP, CK (male), LDH(male), A/G, BUN, GLU (female), CHOL (male) and K+ decreased significantly (P 〈 0.05), while serum TP, TBIL, CR and Ca2+ increased significantly (P 〈 0. 05) ,but serum CHOL, TG, HDL-C and LDL-C were not different. 86.4% (19/22) biochemical and electrolyte indices in RMP were in/or close to the range of normal value of human. Conclusion Most of the blood parameter, blood biochemical and electrolyte indices of RMP were close to human' s normal value.
出处 《中国比较医学杂志》 北大核心 2015年第3期35-41,共7页 Chinese Journal of Comparative Medicine
基金 国家自然科学基金重点项目(81120108003 81330007)
关键词 融水小型猪 血常规 血生化 电解质 Rongshui miniature pig Blood parameters Blood biochemical Electrolyte indices
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