摘要
背景:足部软组织缺损可以采用皮瓣移植技术予以修复。研究显示移植之前应用负压封闭引流技术为皮瓣移植提供良好的组织床,以加快局部的肉芽组织生长。目的:进一步验证足部软组织缺损修复中负压封闭引流技术联合皮瓣移植技术的应用价值。方法:对23例足部软组织缺损患者的临床资料进行回顾性分析,按照修复方案分为观察组12例和对照组11例,分别实施负压封闭引流联合皮瓣移植和非负压封闭引流联合皮瓣移植。结果与结论:观察组的治疗总优良率和皮瓣成活率均显著高于对照组(均P<0.05),移植后随访6个月,23例患者均获得随访,随访率为100%。观察组的皮瓣成活情况良好,且皮瓣呈红黄色,柔软且与周围正常皮肤组织区别不大,效果优于对照。结果表明利用负压封闭引流技术联合皮瓣移植技术来进行足部软组织缺损修复,可以获得良好的修复效果,具有一定的临床应用价值。
BACKGROUND:Foot soft tissue defect can be repaired by skin flap transplantation technology. Vacuum sealing drainage technology can support a good tissue bed for skin flap transplantation, thereby to speed up the local growth of granulation tissue. OBJECTIVE:To further verify the application value of vacuum sealing drainage combined with flap transplantation in foot soft tissue repair. METHODS:A retrospective analysis was performed on the clinical data of 23 cases of foot soft tissue defects, and these 23 cases were divided into observation group (vacuum sealing drainage combined with flap transplantation;n=12) and control group (flap transplantation with no vacuum sealing drainage;n=11) according to the repair scheme. RESULTS AND CONCLUSION:The overal therapeutic excel ent rate and survival rate of the flap in the observation group were significantly higher than those in the control group (both P〈0.05). Al the 23 patients were fol owed up for 6 months, and the fol ow-up rate was 100%. In the observation group, the flaps survived wel with red and yel ow color, which were soft and had no distinct difference from the surrounding normal skin tissues. The therapeutic effect in the observation group was better than that in the control group. These findings indicate that vacuum sealing drainage combined with flap transplantation in foot soft tissue repair can achieve better effects in the repair of foot soft tissue defects and has certain value in clinical application.
出处
《中国组织工程研究》
CAS
北大核心
2015年第7期1133-1137,共5页
Chinese Journal of Tissue Engineering Research