1196例突发性聋预后影响因素分析

Factors Affecting Prognosis in Sudden Deafness: An Analysis of 1196 Cases

目的探讨突发性聋预后的影响因素,为临床治疗及预后判断提供依据。方法对我科收治的1196例(1247耳)突发性聋患者的临床资料进行回顾性分析,将性别、年龄、耳侧、伴发症状、就诊时间、听力损失程度、伴有的基础疾病各因素进行分组,均与预后行χ2检验或Spearman秩相关,将对预后有影响的的因素引入有序Logistic回归分析,得出影响突发性聋预后的相关因素。结果性别、耳侧、耳鸣、耳闷、高血压病、糖尿病、脑梗,各组内预后差异无统计学意义(p>0.05),不同年龄、就诊时间、听力损失程度,是否伴有眩晕、颈椎病、血脂异常,其预后差异有统计学意义(p<0.05);而年龄、就诊时间、听力损失程度、眩晕与预后有相关性(p<0.05)结论就诊时间越短,听力损失程度越轻,不伴眩晕,突聋预后越好,年龄对预后的影响有明显的阶段性。

Objective To study factors influencing prognosis in sudden deafness and provide guidance for clinical treat- ment. Methods Clinical data from 1196 cases （1247 ears） of sudden deafness treated in our department were reviewed and an- alyzed. Factors including sex, age, ear side, concurrent symptoms, treatment time, degree of hearing loss and comorbidities were screened for possible correlation to prognosis using χ^2 test and Spearman＇s rank test. Logistic regression analysis was used to fur- ther analyzed promising factors for their correlation to the prognosis of sudden deafness. Results Sex, ear side, tinnitus, aural fullness, co-existing hypertension, diabetes and cerebral infarction were not correlated to sudden deafness prognosis （p 〉 0.05）. Age, treatment time, degree of hearing loss, presence of vertigo, cervical spondylosis and dyslipidemia showed correlation to prognosis （p 〈 0.05）. Conclusion The prognosis of sudden deafness appears to be better if treatment time is shorter and hear- ing loss is less severe with no vertigo. Age has little influence on the prognosis of sudden deafness.