小面积探头测量人体压痛阈影响因素及正常参考值调查

A SURVEY OF FACTORS IN RELATION TO PRESSURE PAIN MEASUREMENT WITH THE SMALL 0.1-cm^2 PROBE AND ITS NORMAL REFERENCE RANGES IN HEALTHY VOLUNTEERS

目的:分析0.1 cm2小面积探头用于压痛阈测量的影响因素,并计算其正常参考值。方法:以武汉某校男女各50名健康在校大学生为受试者,采用0.1 cm2探头的压力测痛仪,选定右侧前臂两个测痛点,测量两处皮脂厚度、压痛痛觉和耐痛阈值,然后分析影响压痛阈的因素并计算其正常参考值。结果:女性受试者两测痛点处压痛阈值比男性低(P<0.001);各测痛点压痛阈值与测痛点处皮脂厚度(P<0.05)呈正相关;纳入受试者测痛点1处压痛阈值低于测痛点2(P<0.001);通过计算得到不同性别受试者两测痛点处压痛阈值95%正常参考值。结论:0.1 cm2探头用于压痛阈测量受到性别、测痛点深部组织结构及皮脂厚度的影响;本研究所得的正常参考值可为今后0.1 cm2探头用于临床压痛测量提供一定参考。

Objective： To investigate and analyse the possible factors on pressure pain measurement via pressure algometer with the small 0.1 cm2 size probe and to establish the normal reference values of pressure pain threshold（PPT）and pressure pain tolerance（PTO）. Methods：50 male and 50 female healthy volunteers were recruited in this study. PPT and PTO were measured at lateral brachioradialis of lateral elbow joint（point 1） and midpoint of medial and lateral borders of wrist（point 2） with a pressure algometer with the 0.1 cm2 size probe. Cortical thickness of the two points were also measured. Factors affecting pressure pain were measured and the normal reference ranges of PPT and PTO calculated. Results： Females experienced lower PPT and PTO than males at the two points（P〈0.001）. The results of multiple linear regression analysis showed that the PPT and PTO were positively correlated with genders（P〈0.001） and cortical thickness of the test point（P〈0.05）, respectively. PPT and PTO at point 1 was lower than that at point 2（P〈0.001）. In addition, we obtained normal reference values（kg/cm2）of PPT and PTO at the two points of 100 healthy volunteers. Conclusion： Both the PPT and PTO measurement with the 0.1 cm2 size probe might be affected by gender and the cortical thickness of the point. Point 2 might be more appropriate for pressure pain measurement in the clinical studies. The normal reference ranges of the PPT and PTO at the specific points for volunteers could be served as a reference for pressure pain measurement.