H型高血压与缺血性脑卒中预后的关系研究

Relationship research between H-hypertensive and ischemic stroke prognosis

目的研究H型高血压与缺血性脑卒中预后的关系。方法选取本院神经内科中经CT或MRI确诊为缺血性脑卒中的患者630例,对患者进行改良的Rankin评分,并对其相关性进行分析。结果当高同型半胱氨酸界定值为14.5μmol/L,H型高血压与缺血性脑卒中7个月神经功能预后相关(OR=2.58,95%CI=1.23-5.37,P=0.01),是缺血性脑卒中预后的危险因素;高同型半胱氨酸与高血压同时存在时对缺血性脑卒中7个月神经功能预后有正相加交互作用,交互作用指数为1.61。结论 H型高血压与缺血性脑卒中预后的关系和高同型半胱氨酸血症界定值有关。

Objective To study the relationship between H-hypertensive and ischemic stroke prognosis. Methods 630 patients with ischemic stroke diagnosed with CT or MRI were selected. All patients were evaluated with modified Rankin score, and relevance was analyzed. Results With the high homocysteine defining value of 14.5 μmol / L,H-hypertension was related with 7 months neurological prognosis of ischemic stroke（OR=2.58,95% CI=1.23-5.37,P=0.01）, and was a risk factor of ischemic stroke prognosis. The exists of high homocysteine and hypertension had positive sum interaction for7 months neurological prognosis,and the interaction index was 1.61. Conclusion The relationship between H-hypertensive and ischemic stroke prognosis is related to high homocysteine defined values.