摘要
报道1例间质性蕈样肉芽肿并对相关文献进行复习。患者,男,67岁。全身泛发浸润性红斑伴剧烈瘙痒半年。皮肤科检查:躯干、臀部及四肢见片状红斑,上覆少量白色鳞屑,边界欠清,部分皮损呈浸润性。皮损组织病理学检查示:表皮散在少量淋巴样细胞移入,部分移入细胞见核周空晕及小的Pautrier微脓肿。真皮浅层淋巴样细胞苔藓样浸润。真皮中深部胶原纤维间及血管周围单一核细胞、组织细胞及少许嗜酸粒细胞呈间质性浸润,胶原纤维束间隙增宽,并见黏液物质沉积。浸润的淋巴细胞异型不显著,但CD4、CD3、CD2和CD43均阳性表达。
A patient with interstitial mycosis fungoides was reported and the relevant literature was reviewed. A 67-year-old male patient presented with a 6-month history of infiltrated erythematous patch with sever pruritus all over the body. Dermatological examination revealed ill-defined light pink macules with white lamellar scales located on the trunk and buttocks. Some of the lesions were infiltrated. Histopathological examination revealed a small number of mononuclear cell infiltrate in the epidermis, with perinuclear halo in some cells and formation of Pautrier's microabscesses. There were lichenoid infiltrates in the superficial dermis and infiltrates consisting of numerous mononuclear cells, histiocytes and a few eosinophils between collagen fibers and around the vessels in the middle and deep dermis. The clefts between collagen fibers were broadened, where mucin deposits were seen. There was no cytologic atypia in the lymphoid cells and immunohistochemically the cells were positive for CD4, CD3, CD2 and CD43 staining in the superficial and middle dermis.
出处
《中国麻风皮肤病杂志》
2015年第3期152-155,共4页
China Journal of Leprosy and Skin Diseases
关键词
蕈样肉芽肿
间质性蕈样肉芽肿
mycosis fungoides
interstitial mycosis fungoides