急性脑梗死患者ESSEN、NIHSS评分与Fg、DD、vWF Ag水平的关系

Correlation between ESSEN,NIHSSS score and Fg,DD,vWF Ag in Patients with acute cerebral infarction

目的探讨急性脑梗死患者ESSEN、NIHSS评分与纤维蛋白原(Fg)、D-二聚体(DD)及血管性血友病因子抗原(v WF Ag)水平的相关性。方法选取本院2013年6月至2014年3月收治的94例急性脑梗死患者,分别针对病例开展ESSEN卒中风险评分与NIHSS神经功能缺损评分,并依据两项评分结果将患者分为低危、中危、高危以及轻型、中型、重型各三组。针对全部病例均开展Fg、DD与v WF Ag的临床检测,并通过不同评分等级患者的结果比较,探讨临床评分与检验结果的相关性。结果 ESSEN评分中,中危组与高危组的Fg、DD与v WF Ag水平均明显高于低危组,其中以高危组最为显著;NIHSS评分中,中型组与重型组的Fg、DD与v WF Ag水平明显高于轻型组,其中以重型组最为显著,组间比较差异均具有统计学意义(P<0.05)。结论急性脑梗死患者的ESSEN评分、NIHSS评分与Fg、DD、v WF Ag水平存在密切关联,评分结果表现病情越重患者的三项指标水平越高,提示Fg、DD、v WF Ag能够作为急性脑梗死病情程度的评估因子。

Objective To investigate the correlation between ESSEN, NIHSSS score and Fg, DD, vWF Ag in patients with acute cerebral infarction.Methods Selected 94 patients of acute cerebral infarction in our hospital from June 2013 to March 2014.Who were carried out score with ESSEN and NIHSS.Meanwhile, clinical detection level of Fg, DD and vWF Ag.Results In ESSEN score, the level of Fg, DD and vWF Ag in medium-risk group and high-risk group were higher than light-risk group, and high-risk group had the most significant （P〈0.05）.In NIHSS score, the level of Fg, DD and vWF Ag in moderate group and severe group were higher than mild group, and severe group had the most significant（P〈0.05）.Conclusions ESSEN, NIHSS score is closely associated with Fg, DD, vWF Ag in patients with acute cerebral infarction.