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脂代谢紊乱在阿尔茨海默病发病机制中的作用 被引量：9

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摘要 阿尔茨海默病（Alzheimer’s disease,AD）是老年期痴呆最常见的疾病之一。AD临床隐袭起病,表现为认知功能和日常生活能力持续恶化,病理上以老年斑、神经原纤维缠结、神经元丢失及淀粉样血管病等为特征。其病因学和发生机制目前仍然知之甚少。近年来越来越多的研究证实脑内胆固醇代谢紊乱和AD的发病有密切的关系。本文就AD患者脑内胆固醇代谢的改变,
作者 姚恺 祖恒兵
机构地区 上海复旦大学附属金山医院
出处 《神经解剖学杂志》 CAS CSCD 北大核心 2015年第2期261-264,共4页 Chinese Journal of Neuroanatomy
关键词 胆固醇 脂筏 载脂蛋白E 阿尔茨海默病
分类号 R749.16 [医药卫生—神经病学与精神病学]
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参考文献36

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二级参考文献7

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神经解剖学杂志
2015年 第2期

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