Moyamoya病相关眼部症状的临床分析

Clinical analysis of ocular presentations in moyamoya disease

目的探讨与Moyamoya病相关的眼部临床表现、发生机制及其临床意义。方法回顾性分析37例有眼部症状的Moyamoya病患者的临床资料。结果 37例有眼部症状的Moyamoya病患者,单纯以眼部症状首发者8例,眼部症状与其它神经系统症状同时出现的29例;患者眼部症状主要表现为:一过性黑朦、偏盲、视力下降甚至丧失、视野缺损、瞳孔直接/间接对光反射消失、瞳孔大小异常、上睑下垂、眼球运动障碍、眼球疼痛。结论 Moyamoya病眼部症状多样,神经科医生和眼科医生均应掌握Moyamoya病的临床表现及其特点,对于有眼部症状的患者应及时做全面的检查,以免漏诊和误诊。

OBJECTIVE To explore the clinical manifestations and mechanism of ocular symptoms related to moyamoya disease. METHODS The clinical information was analyzed retrospectively in 37 moyamoya disease. RESULTS There were 8 patients examined to simply perform ocular manifestations,while 29 patients had ocular manifestations accompanied by other neurologic symptoms. These ocular signs included amaurosis fugax,hemianopia,de-cline even loss of the visual ability,visual field defect,pupil direct/indirect light reflex,pupil size abnormal,ptosis,ocular dyskinesia and eye pain. CONCLUSIONS The symptoms of moyamoya disease are multiple,which required neurologic physician and ophthalmologist be proficient in the onset characteristics and clinical manifestation. The patients must be diagnosed and treated as soon as possible to avoid misdiagnosis and missed diagnosis,especially for patients with ocular signs.