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ACEI/ARB类降压药物在肿瘤治疗中的临床研究进展 被引量：2

Clinical research progress of ACEI/ARB used in tumor treatment
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摘要 血管紧张素转化酶抑制剂(ACEI)和血管紧张素受体Ⅱ抑制剂(ARB)类药物是临床心脑血管系统常用药物,一些流行病学研究发现其具有抗肿瘤作用。有一些临床研究表明ACEI/ARB类药物在肿瘤合并高血压人群中表现出潜在的抗肿瘤作用。就其最新临床研究进展进行综述。 Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are commonly used in clinical cardiovascular system diseases.Recently,some epidemiological studies found its potential antitumor effect.Several clinical studies showed that ACEI/ARB drugs exerted antitumor effect when used in hypertensive individuals with tumor.Thus,we summarized the latest clinical research progress as follows.
作者 王增 袁梅琴 杨国浓 丁海樱
机构地区 浙江省肿瘤医院药剂科 浙江省肿瘤医院化疗中心
出处 《中国临床药理学与治疗学》 CAS CSCD 2015年第2期230-234,共5页 Chinese Journal of Clinical Pharmacology and Therapeutics
基金 浙江省药学会医院药学专项科研资助项目(2013ZYY06)
关键词 血管紧张素转化酶抑制剂 血管紧张素受体Ⅱ抑制剂 肿瘤 临床研究 angiotensin-converting enzyme inhibitors angiotensin receptor blockers tumor clinical trails
分类号 R73 [医药卫生—肿瘤]
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参考文献28

  • 1Zeng F, Harris RC. Epidermal growth factor, from gene organization to bedside [J]. Semin Cell Dev Biol, 2014, 28(5): 2-11.
  • 2Evans T. Utility of hypertension as a surrogate marker for efficacy of antiangiogenic therapy in NSCLC [J]. Anticancer Res, 2012, 32(11) : 4629- 4638.
  • 3Huang CC, Chan WL, Chen YC, et al. Angioten- sin II receptor blockers and risk of cancer in patients with systemic hypertension [J]. Am J Cardio,2011,107(7): 1028-1033.
  • 4Sjoberg T, Garc'a RodYguez LA, Lindblad M. An- giotensin-converting enzyme inhibitors and risk of e- sophageal and gastric cancer: a nested case-control study [J]. Clin Gastroenterol Hepatol, 2007, 5 (10) : 1160-1166.
  • 5Radulescu D, Buzdugan E, Ciuleanu TE, et al. Can the epirubicin cardiotoxicity in cancer patients be prevented by angiotensin converting enzyme inhibi- tors [J]? J BUON, 2013, 18(4) : 1052-1057.
  • 6Lever AF, Hole DJ, Gillis CR, et al . Do inhibitor so fangio-tensin-I-converting enzyme protect against risk of cancer [J]? Lancet, 1998, 352(9123) : 179- 184.
  • 7Ronquist G, Rodriguez LA, Ruigomez A , et al. Association between captopri, 1 other antihyperten- sive drugs and risk of prostate cancer [J]. Prostate, 2004, 58(1): 50-56.
  • 8Meier CR, Derby LE, Jick SS, et al. Angiotensin- converting enzyme inhibitors, calcium channel blockers, and breast cancer [J]. Arch Intern Med, 2000, 160(3): 349-353.
  • 9Pasternak B, Svanstrom H, Callre'us T, et aI. Use of angiotensin receptor blockers and the risk of cancer[J]. Circulation, 2011, 123(16): 1729-1736.
  • 10Chang CH, Lin JW, Wu LC, et al. Angiotensin re- ceptor blockade and risk of cancer in type 2 diabetes mellitus., a nationwide case-control study[J]. J Clin Oncol, 2011, 29(22): 3001-3007.

同被引文献57

  • 1鲁军,任迪峰,王建中,TANOKURA Masaru.螺旋藻源血管紧张素转化酶抑制肽的纯化和鉴定[J].生物化学与生物物理进展,2010,37(5):568-574. 被引量：12
  • 2YAMAMOTO N. Antihypertensive peptides derived from food proteins[J]. Biopolymers Peptide Science, 1997, 43(2): 129-134.
  • 3CONTRERAS M D M, CARRON R, MONTERO M J, et al. Novel casein-derived peptides with antihypertensive activity[J]. International Dairy Journal, 2009, 19(10): 566-573.
  • 4NORRIS R, POYARKOV A, O' KEEFFE M B, et al. Characterisation of the hydrolytic specificity of Aspergillus niger derived prolyl endoproteinase on bovine r-casein and determination of ACE inhibitory activity[J]. Food Chemistry, 2014, 156(8): 29-36.
  • 5NORRIS R, O' KEEFFE M B, POYARKOV A, et al. Peptide identification and angiotensin converting enzyme (ACE) inhibitory activity in prolyl endoproteinase digests of bovine as-casein[J]. Food Chemistry, 2015, 188(1): 210-217.
  • 6MARUYAMA S, SUZUKI H. A peptide inhibitor of angiotensinI- converting enzyme in the tryptic hydrolysate of casein[J]. Agriculture Biology Chemistry, 1982, 46(5): 1393-1394.
  • 7KOHMURA M, NIO N, ARIYOSHI Y. Inhibition of angiotensin I-converting enzyme by synthetic peptides of human x-casein[J]. Agricultural and Biological Chemistry, 1990, 54(3): 825-836.
  • 8YAMAMOTO N.Antihypertensive peptides derived from food proteins[J]. Biopolymers Peptide Science, 1997, 43(2): 129-134.
  • 9FERREIRA I M P L V O, PINHO O, MOTA M V, et al. Preparation of ingredients containing an ACE-inhibitory peptide by tryptic hydrolysis of whey protein concentrates[J]. International Dairy Journal, 2007, 17(5): 481-487.
  • 10COSTA E L D, GONTHO J A D, NETTO F M. Effect of heat and enzymatic treatment on the antihypertensive activity of whey protein hydrolysates[J]. International Dairy Journal, 2007, 17(6): 632-640.

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中国临床药理学与治疗学
2015年 第2期

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