G试验对霉菌性鼻窦炎患者诊断价值初探

A Preliminary Study of G test＇s Diagnostic Value on Patients with Fungal Sinusitis

目的：探讨血浆G试验检测对诊断霉菌性鼻窦炎（Vs）的价值。方法：Fs确诊患者35例和健康对照组10例，取患者外周血分离血浆，用G试验方法检测各组血浆（1，3）-β-D葡聚糖（BG）浓度。结果：32例真菌球型真菌性鼻窦炎中，28例BG平均浓度37．6±12．9pg／ml，阳性率为87．5％，4例检测值〈5pg／ml；1例急性暴发型检测值为835．2pg／ml，2例慢性侵袭性真菌性鼻窦炎检测值分别为335．2pg／ml、695．2pg／ml。对照组及FS术后检测均〈5pg／ml。结论：FS患者血浆BG水平明显高于对照组患者，提示G试验可作为FS的诊断指标。

Objective： To investigate the value of G test detection of plasma on diagnosing fungal sinusitis （Fs）. Methods： 35 cases of patients diagnosed with Fs and 10 cases of healthy controls. Take isolated peripheral blood plasma of the patients. The plasma is detec- ted by G test methods （ 1,3 ） - β - D - glucan （BG） concentration. Results： Among the 32 cases of fungal ball fungal sinusitis, 28 ca- ses of them has BG average concentration of 37.6 ± 12.9pg / ml. The positive rate is 87.5% ; The detected value of four cases is less than 5 pg / ml; One case of acute patients is 835.2pg / ml; Detected values of two cases of chronic invasive fungal sinusitis are 335.2 pg / ml, 695.2 pg / ml. The detected values of the control group and FS after operation are less than 5 pg / ml. Conclusion： BG plasma levels are significantly higher in patients with FS. We suggest that G test should be used as a diagnostic indicator of FS.