广东凉茶颗粒苷类化学成分研究(Ⅱ)

Study on Glycosides Constituents from Guangdong Liangcha Granules(Ⅱ)

目的：对广东凉茶颗粒中的苷类化学成分进行研究。方法：采用硅胶柱色谱、Sephadex LH-20凝胶柱色谱、ODS等色谱方法进行分离纯化,运用波谱技术和文献对照法鉴定化合物结构。结果：从广东凉茶颗粒甲醇提取物的乙酸乙酯部位和正丁醇部位中共分离得到6个苷类化合物,分别鉴定为：冬青苷B（1）、asprellanosides B（2）、asprellanoside A（3）、4’,5,7-三羟基黄酮-6-O-β-D-吡喃葡萄糖苷（4）、异佛来心苷（5）、3-甲氧基-4’-鼠李糖鞣花酸（6）。结论：其中,化合物1~5为首次从广东凉茶颗粒中分离得到。

Objective： To study the glycosides from Guangdong Liangcha Granules. Methods： The chemical constituents were isolated by various chromatographic techniques and the structures of chemical constituents were identified by spectroscopic analysis and literature. Results： Six compounds were isolated and identified as ilexoside B（1）,asprellanosides B（2）,asprellanoside A（3）,4’,5,7-trihydroxyflavone-6-O-β-D-glucopyranosyl ester（4）,isoviolanthin（5）,3-O-methy-lellagic acid 4’-O-rhamnopyranoside（6）. Conclusion：Compounds 1 ~ 5 are firstly obtained from Guangdong Liangcha Granules.