摘要
"化学前沿"通过化学家的视角,揭示了生物医药研究领域内新的理念和成就。报告中的见解和信息来自汤森路透Integrity数据库。该数据库整合了生物学、化学和药理学信息。2014年6月发布的报告包括有机合成路线展示、研究中的分子骨架、新化合物的作用机制、新研发管线等几个部分,分章别类地阐述了筛选疗效和安全性更好的药物的基本方面,并介绍了帕金森病治疗药物的研究现状。
The Cutting Edge of Chemistry discloses new ideas and achievements in the biomedical research field with the chemist＇s perspective in mind. Insights and information within this report are drawn from Thomson Reuters Integrity, the drug discovery database that combines biology, chemistry and pharmacology information. The report issued June 2014 has been organized into sections,including organic synthesis scheme showcase,scaffolds on the mode,new molecular mechanisms of action and the starling line ,which delineate essential aspects of the search for better and safer drugs.And the research status of orphan drugs has also been introduced.
出处
《药学进展》
CAS
2015年第1期63-72,共10页
Progress in Pharmaceutical Sciences
关键词
生物医药研究
有机合成
分子骨架
帕金森病
biomedical research
organic synthesis
scaffold
Parkinson＇s disease
