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One Craniotomy at the Highest Altitude in the World and Follow-up Study

One Craniotomy at the Highest Altitude in the World and Follow-up Study
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摘要 To the Editor: Here we report a craniotomy under general anesthesia successfully performed at a 4350-m altitude and the patient's follow-up results. To the best of our knowledge, this is one craniotomy carried out at the highest altitude in the world to date.A 21-year-old man occurred spontaneous light headache in the Ali area at a 4350-m altitude in the Tibet autonomous region of China on October 23,2011, and his headache became severe gradually. Three days later, the patient was in a coma with 5 scores (E1V1M3) on the Glasgow Coma Scale (GCS); his left pupil diameter was 5.0 mm and right pupil diameter was 3.0 ram, both direct and indirect light reflex of the bilateral pupils disappeared. Craniocerebral computed tomography (CT) scan indicated a large acute subdural hematoma located in the left fronto-temporo-parietal region, widespread subarachnoid hemorrhage and brain herniation [Figure l a-c]. Emergency treatment was given for the patient in time, including continuous mask oxygen inhalation, strong dehydration (20% mannitol 250 ml + furosemide 10 mg + dexamethasone 5 rag, fast intravenous drip, once per 5 h), and medical hemostasis. To the Editor: Here we report a craniotomy under general anesthesia successfully performed at a 4350-m altitude and the patient's follow-up results. To the best of our knowledge, this is one craniotomy carried out at the highest altitude in the world to date.A 21-year-old man occurred spontaneous light headache in the Ali area at a 4350-m altitude in the Tibet autonomous region of China on October 23,2011, and his headache became severe gradually. Three days later, the patient was in a coma with 5 scores (E1V1M3) on the Glasgow Coma Scale (GCS); his left pupil diameter was 5.0 mm and right pupil diameter was 3.0 ram, both direct and indirect light reflex of the bilateral pupils disappeared. Craniocerebral computed tomography (CT) scan indicated a large acute subdural hematoma located in the left fronto-temporo-parietal region, widespread subarachnoid hemorrhage and brain herniation [Figure l a-c]. Emergency treatment was given for the patient in time, including continuous mask oxygen inhalation, strong dehydration (20% mannitol 250 ml + furosemide 10 mg + dexamethasone 5 rag, fast intravenous drip, once per 5 h), and medical hemostasis.
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2015年第7期993-994,共2页 中华医学杂志(英文版)
基金 This study was supported by a grant from the National Natural Science Foundation of China
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参考文献4

  • 1Kolias AG, Kirkpatrick PJ, Hutchinson PJ. Decompressive craniectomy: Past, present and future. Nat Rev Neurol 2013;9:405-l 5.
  • 2Hunter DJ, Smart JR, Whitton L. Increased capillary fragility at high altitude. Br Med J (Clin Res Ed) 1986:292:98.
  • 3Martin DS, Pate JS, Vercueil A, Doyle PW, Mythen MG, Grocott MP, et al. Reduced coagulation at high altitude identified by thromboelastography. Thromb Haemost 2012;107:1066-71.
  • 4Zafren K. Prevention of high altitude illness. Travel Med Infect Dis 2014;12:29-39.

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