老年女性股骨颈骨折妇科相关危险因素分析

Analysis of the gynecological risk factors of femoral neck fracture with osteoporosis in elderly women

目的探讨老年女性骨质疏松性股骨颈骨折的危险因素,为早期准确预测其骨质疏松股骨颈骨折提供客观依据。方法采用病例对照研究方法,选择150例年龄>60岁的骨质疏松性股骨颈骨折女性患者作为骨折组,同时在周边地区随机选取150例年龄相当的无股骨颈骨折的老年女性作为对照组。通过问卷调查的方法,调查两组年龄、初潮年龄、绝经年龄、怀孕次数、生产次数、母乳喂养时间、体重指数等妇科相关情况。采用Logistic回归分析的方法对影响股骨颈骨折的因素进行分析。结果对照组与骨折组的初潮年龄、绝经年龄、怀孕次数、生产次数、母乳喂养时间、体重指数比较差异均有统计学意义(P<0.05或P<0.01),其中老年女性骨质疏松性股骨颈骨折的发生与初潮年龄、怀孕次数、生产次数、母乳喂养时间呈正相关(P<0.05或P<0.01),与绝经年龄、体重指数呈负相关(P<0.01)。结论初潮晚、绝经早、孕产次数多、母乳喂养时间长、体重指数低可能是老年女性骨质疏松性股骨颈骨折的重要危险因素。

Objective To investigate the risk factors for osteoporosis in elderly women with femoral neck fracture for accurately predicting early femoral neck fracture of osteoporotic and providing an objective basis. Methods 150 osteoporotic femoral neck fracture women older than 60 years were selected as a research group with case-control study.Age-matched 150 cases were randomly selected in the surrounding area without femoral neck fractures as a control group. Through questionnaire survey,including age,menarche age,menopause age,number of pregnancies,number of births,breast feeding time,body mass index and other gynecological relevant circumstances. Logistic regression analysis was used to evaluate the effect. Results The difference of menarche age,menopause age,number of pregnancies,number of births,breastfeeding time,body mass index between the control group and fracture group was statistically significant（ P〈0. 05 or P〈0. 01）. Menarche age,number of pregnancies,the number of births,breastfeeding time were positively related to the femoral neck fracture（ P〈0. 05 or P〈0. 01）,and age at menopause,body mass index was negatively correlated（ P〈0. 01）. Conclusions Late menarche,early menopause,pregnancy more often,longer duration of breastfeeding,low body mass index may be important risk factors for osteoporosis in elderly women with femoral neck fracture.