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老年急性缺血性脑卒中溶栓治疗预后分析 被引量:3

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摘要 目的研究分析影响老年急性缺血性脑卒中患者溶栓治疗预后的因素,为临床治疗提供参考。方法选取2011年10月至2013年8月收住我院神经内科的急性缺血性脑卒中的老年患者81例,所有患者入院确诊后,均给予重组组织型纤溶酶原激活剂(rt—PA)进行静脉溶栓治疗。对患者性别、年龄、人院后动脉内膜中层厚度(intima—media thickness,IMT)、血脂、血糖、血压、血浆致动脉硬化指数(atherogenic index of plasma,AIP)以及既往糖尿病、高血压病和高脂血症病史等基线情况,采用改良Rankin量表(mRS)对患者发病后3个月后的预后情况进行评估,并对mRS评分与上述指标的关系进行分析。结果患者颈动脉IMT、AIP以及发病到溶栓时间在患者预后中具有重要作用,差异有统计学意义P〈0.05。在对上述指标进行Logistic回归分析后显示,AIP和颈动脉IMT与患者预后不良呈正相关(分别OR=9.615,P=0.006;OR=7.623,P=0.012)。结论颈动脉IMT和AIP与老年急性缺血性脑卒中患者溶栓治疗预后密切相关,临床可参考该项指标对患者进行针对性治疗及预防。
作者 张育德
出处 《国际医药卫生导报》 2015年第7期919-920,共2页 International Medicine and Health Guidance News
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参考文献5

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