甲状腺功能异常对妊娠结局的影响分析

Influence of thyroid dysfunction on pregnancy outcome

目的探讨甲状腺功能异常对妊娠结局的影响。方法选取我院收治的甲状腺功能异常产妇185例作为研究对象，设为观察组；选取同期于我院分娩的正常产妇218例，设为对照组，对所有对象临床资料进行回顾性分析，分析甲状腺功能异常对妊娠结局的影响。结果观察组妊娠贫血（Х^2=4．041、P=0．032）、妊娠高血压（Х^2=6．362、P=0．018）、妊娠糖尿病（Х^2=7．048、P=0．028）高于对照组；观察组早产儿（Х^2=4．907、P=0．032）、低体重儿（Х^2=5．107、P=0．028）、流产（Х^2=4．351、P=0．031）不良结局发生率高于对照组；胎儿窘迫（Х^2=0．029、P=1．518）、胎盘早剥（Х^2=0．351、P=I．423）对比差异不明显。结论对于妊娠妇女一定要加强甲状腺功能异常的筛查，注重高危人群，以减少产科并发症，改善妊娠结局。

Objective To evaluate the influence of thyroid dysfunction on pregnancy outcome. Methods 185 puerpera with thyroid dysfunction admitted into our hospital were chosen as study objects and were set as an observation group. And 218 normal puerpera admitted into our hospital during the same period were chosen as a control group. The clinic data of all the objects were retrospectively analyzed. The influence of thyroid dysfunction on pregnancy outcome was analyzed. Results The incidences of anemia （X 2=4.041, P=0.032）, hypertension（x 2=6.362, P=0.018） and the gestational diabetes mellitus （Х^2=7.048, P=0.028） were markedly higher in the observation group than the control group. The incidences of premature infant（Х^2=4.907, P=0.032）, low-birth weight infant （Х^2=5.107, P=0.028）, and misbirth （Х^2=4-351, P=0.031） were markedly higher in the observation group than the control group. There was no statitstical differences in fetal distress（Х^2=0.029, P=l.518）and placental abruption （Х^2=0.351, P=1.423） between the two groups. Conclusions Screening pregnant women＇s thyroid dysfunction should be strengthened. Attention should be paid on the pregnant women at high risk to reduce the obstetrical complications and improve the pregnancy outcome.