艾司西酞普兰和氟西汀治疗抑郁症的疗效对比

Comparison of efficacy of escitalopram and fluoxetine in the treatment of patients with depression

目的：比较艾司西酞普兰和氟西汀治疗抑郁症患者的疗效及对其认知功能的影响。方法：选取2011-2013年间在我院接受治疗的抑郁症患者64例，通过计算机随机分组的方式将其分为实验组和对照组，每组均为32人，实验组患者给予艾司西酞普兰，对照组患者给予氟西汀，比较两组患者的抑郁症治疗效果、认知功能的改变情况及两组的不良反应状况。结果：两组患者在抑郁症的治疗效果及两组的不良反应的发生率上无显著统计学差异，但实验组患者的认知功能改善状况要显著好于对照组。结论：艾司西酞普兰较氟西汀能更好地改善抑郁症患者的认知功能，且安全性较高，值得临床推广。

Objective： To compare efficacy of escitalopram and fluoxetine in the treatment of patients with depression and effect of cognitive function. Methods： 64 cases of patients with depression received treatment in our hospital between 2011-2013,they were divided randomly into experimental and control groups by the computer, each group were 32 people,patients in the experimental group were treated with escitalopram Champlain, the control group were treated with fluoxetine, the effect of the treatment of depressionthe, the change of cognitive function and adverse reactions situation the two groups were compared in two groups. Results： There were no statistically significant differences in the effect of the treatment of depression and the incidence of adverse reactions in the two groups, but the patients＇ cognitive function in the experimental group improved the situation significantly better than the control group. Conclusion：The drug escitalopram can improve cognitive function in patients with depression better than drug fluoxetine, and high security, was worthy of promotion.