女性乳腺疾病患者检测血清PSA水平的临床应用

The clinic application of concentration of PSA in the serum by Electrochemiluminescence on the diagnosis and prognosis of the breast disease

目的:探讨血清前列腺特异性抗原(PSA)在女性乳腺疾病中的诊断价值和预后评估价值。方法:采用电化学发光测定法(ECL)检测47例乳腺癌患者、34例乳腺增生患者和30例正常女性对照组的血清PSA水平。结果:在所有女性血清中均有一定的浓度的PSA水平表达且随着疾病恶性程度的升高其值可明显增高;而在乳腺癌患者中,血清PSA水平与临床分期呈明显的负相关。结论:检测PSA水平在女性乳腺疾病的诊断和预后评估中具有重要的临床应用价值。

Objective： To study the diagnostic and prognostic value of concentration of PSA in serum of the breast disease. Methods： To detect the concentration of serum PSA in 47 patients with breast cancer, 34 women with Benign Disease and 30 healthy women by electrochemiluminescence（ECL）. Result： There were different concentrations of PSA in serum of all women and the more serious the disease ,the higher the value; in the patients with breast cancerz there were negative correlation between the concentration of serum PSA and clinic stage. Conclusion： Examining the concentration of PSA in serum will be important value in the diagnosis and prognosis of the breast cancer.