小剂量右美托咪定辅助颈丛麻醉对患者舒适性的影响

目的:探讨小剂量右美托咪定在颈丛阻滞甲状腺手术中的临床效果辅助颈丛麻醉对患者舒适性的影响方法:择期行颈丛阻滞患者60例,随机分为A、B两组。A组麻醉前泵注右美托咪定1ug/kg,输注时间10min,后改为维持剂量0.4 ug/kg/h;B组不给负荷量,直接给予维持剂量0.4 ug/kg/h泵注,直至手术结束。记录平均动脉压(MAP)、心率(HR)、血氧饱和度(SPO2)的变化以及舒适性视觉模拟评分(VAS)。结果:A组BP表现为先升高后降低,HR减慢,SPO2稍有降低;而B组各指标无明显变化。两组舒适性评分均在8分以上,组间无明显差异。结论:右美托咪定具有良好的镇静镇痛作用,呼吸抑制轻,患者术中安静合作,舒适性高,而小剂量右美托咪定对循环影响更小,是一种较好的麻醉辅助方法。

Objective： To study the Effects of low dose intravenous dexmedetomidine on thyroid gland surgery under cervical plexus block .Methods： Sixty patients under cervical plexus block 1 anesthesia were randomly allocated to two groups. Group A received IV dexmedetomidine 1 μg/kg bolus over 10 min, followed by an infusion of 0.41μg/kg/h for the duration of the surgery. Group B received an infusion of 0.4μg/kg/h only. The MAP, HR, SPO2 andceasing VAS Score were recorded. Results： The BP in group A were decreased at first, and then increased. The HR were decreased. And the SPO2 were decreased slightly. There were no obvious changes in group B. The score of VAS were over eight, without significant differences between the groups Conclusion： Dexmedetomidine has sedative and analgesic effects, without significant respiratory depression. The patients were calm, co-operative and comfortable .The low dose dexmedetomidin has slightly effect on BE which is a better method.