浆细胞性乳腺炎手术时机选择的探讨

Investigation of the Timing of Surgery for Plasma-cell Mastitis

目的:探讨浆细胞性乳腺炎手术时机的选择对其疗效的影响。方法:回顾性分析2008-2013年我科收治的98例浆细胞性乳腺炎手术治疗的患者临床资料,予大剂量激素冲击治疗1周后予分组治疗,其中观察组16例(激素不敏感者)予手术辅助治疗+激素维持治疗,对照组82例(激素治疗有效者)继续予激素维持治疗,观察两组疗效进行临床分析。结果大剂量激素冲击治疗1周后,2组治愈总有效率无明显差异(P>0.05)而在复发率、并发症观察组较对照组明显减少(P<0.05,P<0.01),平均疗程亦明显缩短(P=0.00),观察组在切口感染率上高于对照组(P<0.01)。结论:大剂量激素冲击治疗浆细胞性乳腺炎在症状控制后再行手术治疗可明显降低该病的复发率,减少激素并发症、切口感染率,缩短平均疗程,一定程度上为患者减轻痛苦。

Objective To investigate about plasma-cell mastitis timing of surgery and efficacy. Methods Retrospective analysis of 2008 ~ 2013 in our department from the year for 98 cases with operation of plasma cell mastitis with clinical data. Impact to the large dose hormone therapy in the treatment group after 1 week, observation group 16 cases of hormone is not sensitive to surgical adjuvant treatment ＋ hormone therapy to maintain, control group 82 cases（hormone therapy） effectively continue to hormone therapy to maintain, to observe the curative effect of the two groups in clinical analysis. Results Large dose hormone shock therapy after 1 week, cure the total effective rate in the 2 groups were no signifi cant differences（P〉0.05） in the recurrence rate, complication observed group than the control group decreased significantly（P〈0.05, P〈0.01）, and the average period of treatment also signifi cantly reduced（P = 0.00）, the observation group on the incision infection rate is higher than the control group（P〈0.01）.Conclusion Impact large dose hormone in treatment of plasma cell mastitis in symptom control after surgery can obviously reduce the recurrence of the disease, less complications, hormone incision infection rate, shorten the average period of treatment, to some extent for patients relieve the pain, is worth popularization in clinical application.