高频振荡通气治疗新生儿气胸的疗效观察

Efficacy of high-frequency oscillatory ventilation on neonatal pneumothorax

目的探讨临床有效治疗新生儿气胸的可靠方法,为新生儿气胸的临床研究和治疗实践提供参考和借鉴依据。方法本研究选取2010年12月至2013年12月绵阳市人民医院收治的新生儿气胸患儿92例,随机分成常规呼吸机组和高频呼吸机组,每组46例,分别实施传统常频通气治疗和高频振荡通气治疗。观察并比较两组治疗前后的氧合指数值和动脉/肺泡氧分压比值。结果高频呼吸机组治疗后24 h和48 h氧全指数水平均显著优于常规呼吸机组,差异有统计学意义(t=3.8544,5.7208,P均<0.05);高频呼吸机组治疗后24 h和48 h的动脉/肺泡氧分压比值均显著优于常规呼吸机组,差异有统计学意义(t=6.3553,6.3803,P均<0.05)。结论在临床针对新生儿气胸患儿实施治疗的实践过程中,与传统常频通气治疗方法比较,采用高频振荡通气治疗新生儿气胸的临床治疗效果显著,是临床针对新生儿气胸患儿实施治疗的理想选择之一。

Objective To further investigate a reliable method for the treatment of neonatal pneumothorax,and thus to provide reference for clinical reference and treatment practices for neonatal pneumothorax. Methods The clinical data of 92 patients with neonatal pneumothorax from December 2010 to December 2013 in Mianyang People＇s Hospital were chosen and randomly divided into the conventional breathing machine group and high-frequency breathing group,with 46 cases in each group.They were taken with traditional normal frequency ventilation therapy and high-frequency oscillatory ventilation therapy separately. The oxygenation index value and arterial / alveolar oxygen tension rates for the two groups before and after conventional ventilator therapy and high-frequency ventilator therapy were observed and compared. Results The oxygenation index values for the two groups of 24 h and 48 h after treatment were compared. The statistical data showed that the level of children with high-frequency was significantly better than the children with regular breathing group,and the differences were significant（ t = 3. 8544,5. 7208,P〈0. 05）. The arterial / alveolar oxygen tension rate for the two groups after treatment at 24 h and 48 h were also compared. The statistics indicators showed that the level of the high-frequency group was significantly superior to the conventional children,and the differences of the two groups were significant（ t = 6. 3553,6. 3803,P〈0. 05）. Conclusion In clinical practice for the treatment of children with neonatal pneumothorax implementation,the clinical effect of high frequency oscillatory ventilation treatment of neonatal pneumothorax is significant in comparison with the conventional constant-frequency ventilation therapy,and it is a good choice for the treatment of neonatal pneumothorax.