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长链非编码RNA在肝癌中的研究进展 被引量:2

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摘要 长链非编码RNA(long non-coding RNA,lncRNA)是一类转录本长度超过200个核苷酸、少有或无蛋白质编码功能的RNA分子。lncRNA在表观遗传学水平、转录水平和转录后水平调控基因表达,广泛参与机体的生理和病理过程;并与物种进化、胚胎发育、代谢调节以及肿瘤发生、发展密切相关。本文对lncRNA在肝癌中的最新研究进展作一综述,以期为肝癌临床诊断与治疗提供新的思路。
出处 《临床检验杂志》 CAS CSCD 2015年第3期207-210,共4页 Chinese Journal of Clinical Laboratory Science
基金 国家自然科学基金(81271920) 江苏省"科技兴卫工程"创新团队项目(LJ201133)
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