器官形态发生探索Ⅰ:生物电与形态发生

Exploration of organ morphogenesis Ⅰ: Bioelectricity and morphogenesis

器官形态发生是生命体发育成其固有的三维立体结构并维持其形状的过程,这个过程需要形态发生信息的指导.形态发生信息包含3个方面:1)位置信息;2)预期模式信息;3)表观遗传信息.形态发生信息的实质及其作用机制是理解形态发生的首要条件.在低等动物中研究发现,生物电作为一个密码系统编码着形态发生,是形态发生信息的实质.该文综述了器官形态发生场与器官形态发生、生物电在编码器官形态发生方面的最新研究进展,并基于日常生活中用电作为密码系统的实例,提出了生命体内存在生物电高级运行方式的假设.相信在不久的将来,随着生物电密码的破解,人为控制器官形态发生将成为现实.

Summary Morphogenesis is a biological process that involves the shape development and pattern maintenance of an organism . Morphogenetic information is needed for morphogenetic primordial developing to construct an appropriate three‐dimension （3D） structure , which includes three aspects ：positional information , prepatterning information , and epigenetic information . The essence and mechanism of morphogenetic information is the primary condition to understand morphogenesis . This paper reviews the latest research progress of morphogenetic field , bioelectricity and organ morphogenesis .