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A novel synthesis route to furo[3,2-a]carbazole 被引量:3

A novel synthesis route to furo[3,2-a]carbazole
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摘要 In this paper, we report a novel approach to the heteroaryl-condensed nuclei of natural furo[3,2- a]carbazole alkaloids. Our synthetic studies use N-phthaloyl tryptophan methyl ester as starting material and zinc ion mediated transamination reaction as the key step. This work also implicated a novel strategy to assemble other [a]-fused carbazoles. In this paper, we report a novel approach to the heteroaryl-condensed nuclei of natural furo[3,2- a]carbazole alkaloids. Our synthetic studies use N-phthaloyl tryptophan methyl ester as starting material and zinc ion mediated transamination reaction as the key step. This work also implicated a novel strategy to assemble other [a]-fused carbazoles.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2015年第3期282-284,共3页 中国化学快报(英文版)
基金 supported by NSFC (No.21102026) Qiankehe [2011] 3002 West Light Foundation of the Chinese Academy of Sciences
关键词 Synthesis Furo[3 2-a]carbazole Transamination Synthesis Furo[3,2-a]carbazole Transamination
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  • 1A.W. Schmidt, K.R. Reddy, H.J. Kn?lker, Occurrence, biogenesis, and synthesis of biologically active carbazole alkaloids, Chem. Rev. 112 (2012) 3193-3328.
  • 2C. Ito, H. Furukawa, New carbazole alkaloids from Murraya euchrestifolia Hayata, Chem. Pharm. Bull. 38 (1990) 1548-1550.
  • 3T.S. Wu, S.C. Huang, P.L. Wu, Pyrano-and furocarbazole alkaloids from the root bark of Clausena excavate, Heterocycles 45 (1997) 969-973.
  • 4For review see: W. Fr?hner, M.P. Krahl, K.R. Reddy, et al., Transition metal complexes in organic synthesis, part 73, Synthetic routes to naturally occurring furocarbazoles, Heterocycles 63 (2004) 2393-2407.
  • 5Y. Xia, Z.X. Liu, Q. Xiao, et al., Rhodium(11)-catalyzed cyclization of bis(N-tosylhydrazone) s: an efficient approach towards polycyclic aromatic compounds, Angew. Chem. Int. Ed. 51 (2012) 5714-5717.
  • 6S.C. Pelly, C.J. Parkinson, W.A.L. van Otterlo, et al., Metathesis reactions for the synthesis of ring-fused carbazoles, J. Org. Chem. 70 (2005) 10474-10481.
  • 7S. Ohta, M. Okamoto, Synthesis of carbonyl compouds via biogenetic-type transamination reaction, Synthesis 9 (1982) 756-758.
  • 8A. Papanikos, J. Rademann, M. Meldal, a-Ketocarbonyl peptides: a general approach to reactive resin-bound intermediates in the synthesis of peptide isosteres for protease inhibitor screening on solid support, J. Am. Chem. Soc. 123 (2001) 2176-2181.
  • 9E.J. Corey, D.Y. Gin, R.S. Kania, Enantioselective total synthesis of ecteinascidin 743, J. Am. Chem. Soc. 118 (1996) 9202-9203.
  • 10S. Liu, Y.M. Cui, F.J. Nan, Total synthesis of the originally proposed and revised structures of scleritodermin A, Org. Lett. 10 (2008) 3765-3768.

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