女性人乳头瘤病毒感染、疗效与性伴关系的相关性研究

The correlation study of papilloma virus infection,curative effect and sexual partner relationship of the female

目的:初步探讨女方发现感染人乳头瘤病毒,其性伴HPV感染对女性治疗疗效的影响。方法:门诊体检发现人乳头瘤病毒的女性患者,对其性伴进行人乳头瘤病毒检测;而后将性伴无HPV感染的女性患者分为A组(68例),配偶有HPV感染女性患者分为B组(68例)、C组(68例),三组进行相同治疗,但A、C组患者禁止性生活或采取避孕套性生活,B组正常、非避孕套性生活。结果:女方体检发现人乳头瘤病毒感染的358例患者,其性伴HPV感染为296例;A组和C组疗效明显优于B组(P<0.05),有统计学差异;A组与C组疗效相似(P>0.05),没有统计学差异。结论:女性人乳头瘤病毒感染患者,其性伴HPV感染率高,且女性的治疗疗效与性伴感染与否有密切关系。

Objectives： To study the situation of women infected with human papilloma virus and the efficacy of the treatment when their sexual partners were infected. Method： We selected women who were found infected with human papilloma virus in the clinic and gave their sexual partners papilloma virus detection. The female patients were divided into three groups,group A（ 68 cases） whose sexual partners were not infected by HPV,group B（ 68 cases） and C（ 68 cases） whose sexual partners were infected by HPV. All the patients were treated by the same way. The patients in group A,C were prohibited to have sex with their partners; the patients in the group B had normal sex life with their partners even without condom. Result： The number of woman who were found infected by human papilloma virus was 358. The number of their sexual partners who were infected by human papilloma was296; the curative effect of Group A and group C was better than that of group B（ P〈 0. 05）,with statistically significant difference. The curative effect of Group A and group C was similar,with no statistical differences（ P〈 0. 05）. Conclusion： For women who were infected by HPV,the HPV infection rate of their partner is high. And the treatment efficacy is closely related with the infection situation of their sexual partners.