酒精依赖者心肌酶与心电图异常的临床观察与分析

CLINICAL OBSERVATION AND ANALYSIS ON CARDIAC ENZYMES AND ELECTROCARDIOGRAM ABNORMALITIES AMONG ALCOHOL DEPENDENT CASES

目的:探讨酒精依赖者心肌酶与心电图改变及影响因素。方法:对60例酒精依赖者及40例正常人的心肌酶与心电图进行对照分析,并调查酒依赖者饮酒年限、日饮酒量对其心肌酶与心电图改变的影响。结果:酒精依赖组心肌酶LDH、AST、!-HBDH、CK、CK-MB均显著高于正常组(P<0.01);同时酒精依赖组心电图异常率显著高于正常组(P<0.01),其中左心室高电压9例(15%)、ST-T改变26例(43.33%),高于正常组(P<0.05)。饮酒年限、日饮酒量对心电图改变差异无统计学意义(P>0.05),日饮酒量对心肌酶改变差异无统计学意义(P>0.05);饮酒年限>10 a者CK高于饮酒年限<10 a者,差异有统计学差异意义(P<0.05)。结论:长期酒精摄入会影响心血管系统,导致心肌损害与心电图异常。

ABSTRACT Objective： To investigate changes and influence factors of cardiac enzymes and electrocardiogram（ECG） among alcohol dependent cases. Methdos： Comparative analysis was made on cardiac enzymes and ECG among 60 alcohol dependent cases and 40 normal cases. Influence factors such as drinking age and daily alcohol consumption on cardiac enzymes and ECG changes were investigated. Results：Cardiac enzymes LDH ,AST,α -HBDH, CK and CK -MB of the alcohol dependence group were significantly higher than the normal group（P 〈 0.01 ）. Meanwhile,ECG abnormality rate of the alcohol dependence group was significantly higher than the normal group （ P 〈 0.01 ）, with 9 cases with high voltage left ventricle（ 15% ） and 26 cases with ST - T changes（43.33% ） ,which were higher than the normal group （ P 〈 0.05 ）. There were no statistical differences on drinking age and daily alcohol consumption on ECG changes （P 〉 0. 05 ）. There was no statistical difference on daily alcohol consumption and cardiac enzymes change（ P 〉 0.05 ）. CK of cases with more than 10 -year drinking age were higher than that of those with less than 10 - year drinking age（P 〈0.05）. Conclusion：Long - term alcohol intake affects the cardiovascular systeni, and leads to myocardial damage and abnormal ECG.