摘要
目的:了解福建省南平市第二医院(以下简称"我院")外科围术期质子泵抑制剂的使用情况,为临床合理使用质子泵抑制剂提供参考。方法:统计2014年7月我院外科出院的209例手术患者的资料,对质子泵抑制剂的应用种类、给药时间、剂量、疗程及使用金额进行统计分析。结果:209例手术患者中,82例使用了质子泵抑制剂,占39.23%;其中,29例患者为不存在应激性溃疡风险因素而用药,占35.37%。使用质子泵抑制剂的剂型均为注射剂,无口服制剂;用药频次为1日1或2次;用药剂量为常规剂量;用药时间1-25 d,平均用药时间5.3 d,用药3 d以上的有51例,占62.2%。质子泵抑制剂销售金额(31 421.12元)占药品总销售金额(463 165.64元)的6.78%,占住院总费用(1 669 968.73元)的1.88%;其中,不存在应激性溃疡风险而使用的质子泵抑制剂销售金额(5 606.00元)占质子泵抑制剂销售金额的17.84%。结论:我院外科围术期无适应证使用质子泵抑制剂的比例较高,质子泵抑制剂使用时间偏长。
OBJECTIVE: To investigate the use of proton pump inhibitors( PPIs) in surgery department of FujianNanping Municipal Second Hospital( hereinafter referred to as "our hospital") for reference of the ratioal use of PPIs.METHODS: The data of 209 surgical patients discharged from our hospital during July 2014 were collected for statistical anlysis regarding the drug types,administration time,dose,course of treatment,and consumption sum.RESULTS: Of the total 209 cases,82( 39. 23%) used PPIs,of which,29( 35. 37%) used PPIs without risk factors for stress ulcer. All the PPIs used were injections rather than oral formulations; PPIs were used at frequency of q. d or b. i. d. at conventional dose for duation of 1-25 days( 53 days on average). 51 cases( 62. 2%) used PPIs for duration of at least 3 days. The consumption sum of PPIs( 31 421. 12 yuan) represented 6. 78% of total drug consumption sum( 463 165. 64 yuan) and 1. 88% of total hospitalization cost( 1 669 968. 73 yuan). The consutmpion sum of PPIs in patients without showing risk factors for stress ulcer( 5 606. 00 yuan) representing 17. 84% of total consumption sum for PPIs. CONCLUSIONS: The proportion of the surgical patients receiving PPIs without indication in our hospital was on the high side and and duration of its administration is long.
出处
《中国医院用药评价与分析》
2015年第3期326-329,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
围术期
质子泵抑制剂
调查分析
应激性溃疡
Perioperative
Proton pump inhibitor
Investigation and analysis
Stress ulcer