1Foulkes WD, Shuen AY. In brief: BRCA1 and BRCA2 [J]. J Pathol, 2013, 230(4): 347-349.
2Sharan SK, Morimatsu M, Albrecht U, et al. Embryonic le- thality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2[J]. Nature, 1997, 386(6627): 804- 810.
3Chen PL, Chen CF, Chen Y, et al. The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment[J]. Proc Natl Acad Sci USA, 1998, 95(9): 5287-5292.
4Chen J, Silver DP, Walpita D, et al. Stable interaction be- tween the products of the BRCA1 and BRCA2 tumor sup- pressor genes in mitotic and meiotic cells[J]. Mol Cell, 1998, 2(3): 317-328.
5Yu VP, Koehler M, Steinlein C, et al. Gross chromosom-al rearrangements and genetic exchange between nonho- mologous chromosomes following BRCA2 inactivation [J]. Genes Dev, 2000, 14(11): 1400-1406.
6Cox MM, Goodman MF, Kreuzer KN, et al. The importance of repairing stalled replication forks[J]. Nature, 2000, 404 (6773): 37-41.
7Moynahan ME, Chiu JW, Koller BH, et al. Brcal con- trois homology-directed DNA repair[J]. Mol Cell, 1999, 4(4): 511-518.
8Tutt A, Bertwistle D, Valentine J, et al. Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double- strard breaks occurring between repeated se- quences[J]. EMBO J, 2001, 20(17): 4704-4716.
9Xia B, Sheng Q, Nakanishi K, et al. Control of BRCA2 cellular and clinical functions by a nuclear partner,PALB2[J]. Mol Cell, 2006, 22(6): 719-729.
10Sy SM, Huen MS, Chen J. PALB2 is an integral com- ponent of the BRCA complex required for homologous recombination repair[J]. Proc Natl Acad Sci USA, 2009, 106(17): 7155-7160.
7Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016 [ J]. CA Cancer J Clin, 2016, 66 (1): 7-30.
8Son BH, Ahn SH, Kim SW, et al. Prevalence of BRCA1 and BRCA2 mutations in non-familial breast cancer patients with high risks in Korea: the Korean Hereditary Breast Cancer (KOHBRA) Study [ J ]. Breast Cancer Res Treat, 2012, 133 (3): 1143-1152.
9Roy R, Chun J, Powell SN. BRCA 1 and BRCA2 : different roles in a common pathway of genome protection [ J]. Nat Rev Cancer, 2012, 12 (1) : 68-78.
10Cichon MA, Degnim AC, Visscher DW, et al. Microenvironmental influences that Drive Progression from Benign Breast Disease to Inva- sive Breast Cancer [J]. J Mammary Gland Biol Neoplasia, 2010, 15 (4) : 389-397.