摘要
湿性年龄相关性黄斑变性是年龄相关性黄斑变性的晚期阶段,可导致80%以上患者重度视力丧失,目前临床上诊断主要依靠相干光断层扫描和荧光素眼底血管造影等形态学检查手段,而眼底自发荧光(fundus autofluorescence,FAF)成像技术作为一种非侵入性检测手段,能反应脂褐质的分布及视网膜色素上皮层的活性,已逐渐成为湿性年龄相关性黄斑变性诊治中的观测指标之一.
Wet age-related macular degeneration (wAMD),the advanced stage of age-related macular degeneration (AMD),can lead to severe visual loss in more than 80% patients.At present,its diagnosis mainly depends on the morphological examinations,such as optical coherence tomography (OCT)and fundus fluorescein angiography (FFA).As a noninvasive examination,fundus autofluorescence (FAF) imaging has gradually become one of the observable indicators of wAMD,which can reflect the distribution of lipofuscin and the activity of retinal pigment epithelium (RPE).
出处
《国际眼科纵览》
2015年第1期25-29,共5页
International Review of Ophthalmology
基金
山西省科技攻关项目(20090311063)