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眼底自发荧光技术在湿性年龄相关性黄斑变性诊断中的应用 被引量:5

Application of fundus autofluorescence in diagnosis of wet age-related macular degeneration
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摘要 湿性年龄相关性黄斑变性是年龄相关性黄斑变性的晚期阶段,可导致80%以上患者重度视力丧失,目前临床上诊断主要依靠相干光断层扫描和荧光素眼底血管造影等形态学检查手段,而眼底自发荧光(fundus autofluorescence,FAF)成像技术作为一种非侵入性检测手段,能反应脂褐质的分布及视网膜色素上皮层的活性,已逐渐成为湿性年龄相关性黄斑变性诊治中的观测指标之一. Wet age-related macular degeneration (wAMD),the advanced stage of age-related macular degeneration (AMD),can lead to severe visual loss in more than 80% patients.At present,its diagnosis mainly depends on the morphological examinations,such as optical coherence tomography (OCT)and fundus fluorescein angiography (FFA).As a noninvasive examination,fundus autofluorescence (FAF) imaging has gradually become one of the observable indicators of wAMD,which can reflect the distribution of lipofuscin and the activity of retinal pigment epithelium (RPE).
出处 《国际眼科纵览》 2015年第1期25-29,共5页 International Review of Ophthalmology
基金 山西省科技攻关项目(20090311063)
关键词 年龄相关性黄斑变性 湿性 眼底自发荧光 age-related macular degeneration,wet fundus autofluorescence
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  • 1American Academy of Ophthalmology Retina Panel.Preferred Practice Pattern@Guidelindes:age-related macular degeneration EB/OL I.San Francisco,CA:Ameriean Academy of Ophthalmology (AAO),2008.
  • 2Schmidt-Erfurth UM,Richard G,Augustin A,et al.Guidance for the treatment of neovascuiar age-related macular degeneration.Acta Ophthalmol Scand,2007,85 (5):486-494.
  • 3Age-Related Eye Disease Study Research Group.A randomized,placebo-controlled,clinical trial of high-dose supplementation with vitamins C and E,beta carotene,and zinc for age-related macular degeneration and vision loss:AREDS report no 8.Arch Ophthalmol,2001,119(10):1417-1436.
  • 4Rattner A,Nathans J.Macular degeneration:recent advances and therapeutic opportunities.Nat Rev Neurosci,2006,7 (11):860-872.
  • 5Lu H,Lu Q,Gaddipati S.IKK2 Inhibition attenuates laser-induced choroidal neovascularization.PLoS One,2014,9 (1):e87530.
  • 6Yoneyama S,Sakurada Y,Mabuchi F.Genetic and clinical factors associated with reticular pseudodrusen in exudative age-related maculardegeneration.Graefes Arch Clin Exp Ophthalmol,2014,252(9):1435-1441.
  • 7Smith W,Assink J,Klein R,et al.Risk factors for age-related macular degeneration:pooled findings from three continents.Ophthalmology,2001,108(4):697-704.
  • 8The Eye Diseases Prevalence Research Group.Prevalence of agerelated macular degeneration in the United States.Arch Ophthalmol,2004,122(4):564-572.
  • 9Li Y,Xu L,Wang YX.Prevalence of age-related maculopathy in the adult population in China:the Beijing eye study.Am J Ophthalmol,2008,146(2):329.
  • 10邹海东,张晳,许迅,汪枫桦,张世杰.上海市静安区曹家渡街道年龄相关性黄斑变性的患病率调查[J].中华眼科杂志,2005,4(1):15-19. 被引量:107

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