子宫肌瘤发病的相关危险因素Logistic回归分析

Study on the high-risk factors for patients with uterine myoma: a Logistic regression analysis

目的分析子宫肌瘤发病特点,探讨其发病的相关危险因素,为临床诊断与防治提供依据。方法选取2010年5月至2014年5月于本院治疗的216例子宫肌瘤患者的临床资料,采用1∶1病例对照研究进行调查分析,通过单因素分析与Logistic回归模型分析子宫肌瘤发病的相关危险因素。结果两组研究对象在初婚年龄、流产次数、累计哺乳时间方面比较差异均具有显著性(P<0.05)。初婚年龄晚、流产次数多是子宫肌瘤发病危险因素,而累计哺乳时间长可明显降低子宫肌瘤的发病风险。肉类的摄入量多会增加子宫肌瘤的发病风险;豆制品、蔬菜及水果摄入量多和体育锻炼次数增加可降低子宫肌瘤的发病风险。合并乳腺增生、慢性妇科炎症、一级亲属中患有子宫肌瘤者可明显增加其子宫肌瘤发病风险。结论减少流产次数、延长累计哺乳时间、多摄入豆制品与水果蔬菜、增加体育锻炼均是降低子宫肌瘤发病的保护因素,而合并乳腺增生、慢性妇科炎症、一级亲属患病情况是女性罹患子宫肌瘤的高危因素。

Objective To analyze the clinical characteristics of hysteromyoma and study its related risk factors so that it could provide a certain basis for the clinical diagnosis and prevention. Method Collected clinical data of 216 patients with uterine ifbroids treated in our hospital from May 2010 to May 2014, used 1：1 case-control study investigation and analysis, through the single factor analysis and Logistic regression model analysis to analyze uterine ifbroids related risk factors. Result There were statistically signiifcant difference in the age of first marriage, number of abortions, accumulative total lactation time between two groups of subjects （P〈0.05）. The older of marriage age, more times of abortion increased the risk of uterine ifbroids, while the longer accumulative lactation time obviously reduced the risk of uterine ifbroids. Intaking of more meat increased the risk of uterine ifbroids;intaking of more soy foods, vegetables and fruits, more physical exercise often could reduce the risk of uterine ifbroids. Complicated with mammary gland hyperplasia, chronic gynaecologic inlfammatory disease, ifrst-degree relatives of patients with uterine ifbroids could signiifcantly increase the risk of the incidence of uterine fibroids. Conclusion Both reduction of abortion times and extending lactation time, both intaking more soy foods, fruits, vegetables and increasing physical exercise are protection factors of uterine ifbroids, while mammary gland hyperplasia, chronic gynaecologic inlfammation, ifrst-degree relatives suffering from uterine ifbroids might be the high risk factors of uterine ifbroids.