中西医结合治疗细菌性腹泻84例疗效观察

Clinical efficacy of integrated TCM and western medicine in the treatment of 84 cases of bacterial diarrhea

目的探讨中西医结合治疗细菌性腹泻的临床疗效及不良反应情况。方法 168例细菌性腹泻患儿随机分为对照组和治疗组2组,每组84例。对照组给予西药十六角蒙脱石散治疗,3 g/次;治疗组在对照组基础上加服中药汤剂,3次/d,7 d为1个疗程。1个疗程后观察并记录大便性状、次数和体温等指标。结果对照组总有效率为76.19%,治疗组为89.29%,2组比较差异有统计意义(P<0.05)。治疗组患儿体温恢复正常时间,停止腹泻时间,血常规、大便常规恢复正常时间以及大便培养转阴时间均显著低于对照组,2组比较差异有统计意义(P<0.05)。治疗期间和治疗后2组患儿均未出现严重不良反应。结论十六角蒙脱石散联合中药复方治疗细菌性腹泻效果显著,可尽早改善临床症状,安全可靠,值得推荐作为临床细菌性腹泻的治疗药物。

Objective To investigate the clinical efficacy and adverse reactions of integrated TCM and western medicine in the treatment of bacterial diarrhea. Methods 168 cases of bacterial diarrhea patients were randomly divided into control group and treatment group,84 cases in each group. The control group were treated with western medicine Smecta,3g each time,and the treatment group were treated with TCM decoction based on the above treatment,3 times a day,7 days as a course of treatment. Observation and records were made about the stool property,its frequency and body temperature index. Results The overall response rate of the control group was 78.57%,and that of the treatment group was 89.29%,the differences of the two groups were highly statistically significant（ P〈0.05）. The temperature recovery time,diarrhea receding time,the recovery time of blood routine and stool and the negative turning of stool were significantly shorter than those of the control group,with significant statistical difference（ P〈0.05）. Severe adverse reactions did not occur during and after the treatment. Conclusion Smecta combined with TCM is significantly effective in the treatment of bacterial diarrhea. It can early improve the clinical symptoms,being save and reliable,worthy of recommendation as a common clinical bacterial diarrhea treatment.