慢性咳嗽与阻塞性睡眠呼吸暂停低通气综合征相关性研究进展

Association between chronic cough and obstructive sleep apnea hypopnea syndrome

慢性咳嗽是以咳嗽为唯一或主要症状,咳嗽持续时间超过8周、无吸烟史且肺部影像学检查无异常的咳嗽.慢性咳嗽对患者的工作、生活和社会活动均造成严重的影响.常见的病因包括：咳嗽变异性哮喘、上气道咳嗽综合征、嗜酸粒细胞性支气管炎、胃食管反流疾病等.近年来多项研究提示OSAHS与慢性咳嗽之间存在一定的相关性,经过无创呼吸机治疗OSAHS可明显改善慢性咳嗽的症状.本文就OSAHS与慢性咳嗽的相关性及治疗进展作一综述.

The chronic cough is like that cough is the only or main symptom,the duration of cough is more than 8 weeks,and there is no smoking and normal chest radiographs.The chronic cough has an influence on work,life and social activities of patients.The most common causes of chronic cough consist of cough variant asthma,gastro-oesophageal reflux,upper airway cough syndrome and eosinophilic bronchitis,etc.Recent reports indicate an association between unexplained chronic cough and obstructive sleep apnea hypopnea syndrome （OSAHS） and can be effectively treated by continuous positive airway pressure therapy.This article makes a summary of correlation and treatment progress between OSAHS and chronic cough.